Anti-IRF8 Antibody (Monoclonal, 34I16)

Product Name

Anti-IRF8 Antibody (Monoclonal, 34I16)

View all IRF8 Antibodies

SKU/Catalog Number

M00638

Size

100 μl/vial

Form

Liquid

Description

Boster Bio Anti-IRF8 Antibody (Monoclonal, 34I16) catalog # M00638. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IRF8 Antibody (Monoclonal, 34I16) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00638)

Host

Rabbit

Contents

Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Monoclonal

Clone Number

34I16

Immunogen

Recombinant protein within human IRF8 aa 83-424.

Reactive Species

M00638 is reactive to IRF8 in Human, Mouse

Calculated molecular weight

48.4 kDa

Background of IRF8

Interferon regulatory factor 8(IRF8) also known as Interferon consensus sequence-binding protein(ICSBP), is a protein that in humans is encoded by the IRF8 gene. By genomic sequence analysis, the IRF8 gene is mapped to chromosome 16q24.1. Interferon consensus sequence-binding protein(ICSBP) is a transcription factor of the interferon(IFN) regulatory factor(IRF) family. The IRF family proteins bind to the IFN-stimulated response element(ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the decision for a common myeloid progenitor(CMP) to differentiate into a monocyte precursor cell.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M00638 is guaranteed for Flow Cytometry, IP, IF, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 1:500-2000
Immunocytochemistry/Immunofluorescence, 1:50-200
ImmunoPrecipitation, 1:50
Flow Cytometry (Fixed), 1:50-200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

See full target information IRF8

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