Anti-Monoamine Oxidase B/MAOB Antibody

Monoamine Oxidase B antibody

Boster Bio Anti-Monoamine Oxidase B/MAOB Antibody catalog # PA1649. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

Product Info Summary

SKU: PA1649
Size: 100 μg/vial
Reactive Species: Mouse, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-Monoamine Oxidase B/MAOB Antibody

View all Monoamine Oxidase B Antibodies

SKU/Catalog Number

PA1649

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Monoamine Oxidase B/MAOB Antibody catalog # PA1649. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Monoamine Oxidase B/MAOB Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1649)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of mouse MAOB, identical to the related rat sequence.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1649 is reactive to MAOB in Mouse, Rat

Applications

PA1649 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

59 kDa

Calculated molecular weight

58.763kDa

Background of Monoamine Oxidase B

MAOB (MONOAMINE OXIDASE B), also called MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, By Heat
Western blot, 0.1-0.5μg/ml, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For MAOB (Source: Uniprot.org, NCBI)

Gene Name

MAOB

Full Name

Amine oxidase [flavin-containing] B

Weight

58.763kDa

Superfamily

flavin monoamine oxidase family

Alternative Names

adrenalin oxidase; amine oxidase [flavin-containing] B; EC 1.4.3; EC 1.4.3.4; MAO, brain; MAO, platelet; MAO-B; MGC26382; monoamine oxidase B; Monoamine oxidase type B; tyramine oxidase MAOB monoamine oxidase B amine oxidase [flavin-containing] B|MAO, brain|MAO, platelet|MAO-B|adrenalin oxidase|monoamine oxidase type B|tyramine oxidase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MAOB, check out the MAOB Infographic

MAOB infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MAOB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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6 Customer Q&As for Anti-Monoamine Oxidase B/MAOB Antibody

Question

Is a blocking peptide available for product anti-Monoamine Oxidase B/MAOB antibody (PA1649)?

Verified Customer

Verified customer

Asked: 2020-04-29

Answer

We do provide the blocking peptide for product anti-Monoamine Oxidase B/MAOB antibody (PA1649). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2020-04-29

Question

I would like to test anti-Monoamine Oxidase B/MAOB antibody PA1649 on rat liver for research purposes, then I may be interested in using anti-Monoamine Oxidase B/MAOB antibody PA1649 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2020-01-27

Answer

The products we sell, including anti-Monoamine Oxidase B/MAOB antibody PA1649, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2020-01-27

Question

See attached the WB image, lot number and protocol we used for liver using anti-Monoamine Oxidase B/MAOB antibody PA1649. Please let me know if you require anything else.

C. Yang

Verified customer

Asked: 2019-12-31

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-12-31

Question

My question regarding product PA1649, anti-Monoamine Oxidase B/MAOB antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?

Verified Customer

Verified customer

Asked: 2019-10-15

Answer

It is not recommended storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free PA1649 anti-Monoamine Oxidase B/MAOB antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.

Boster Scientific Support

Answered: 2019-10-15

Question

Thanks for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for liver using anti-Monoamine Oxidase B/MAOB antibody PA1649. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2017-12-26

Answer

I appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2017-12-26

Question

Would anti-Monoamine Oxidase B/MAOB antibody PA1649 work on canine IHC with liver?

T. Li

Verified customer

Asked: 2016-07-06

Answer

Our lab technicians have not tested anti-Monoamine Oxidase B/MAOB antibody PA1649 on canine. You can run a BLAST between canine and the immunogen sequence of anti-Monoamine Oxidase B/MAOB antibody PA1649 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated canine samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in canine liver in IHC, you can get your next antibody for free.

Boster Scientific Support

Answered: 2016-07-06

Order DetailsPrice
PA1649

100μg

$370
PA1649-10ug

10μg sample (liquid)

$99
PA1649-Biotin

100 μg Biotin conjugated

$570
PA1649-Cy3

100 μg Cy3 conjugated

$570
PA1649-Dylight488

100 μg Dylight488 conjugated

$570
PA1649-Dylight550

100 μg Dylight550 conjugated

$570
PA1649-Dylight594

100 μg Dylight594 conjugated

$570
PA1649-FITC

100 μg FITC conjugated

$570
PA1649-HRP

100 μg HRP conjugated

$570
PA1649-APC

100 μg APC conjugated

$670
PA1649-PE

100 μg PE conjugated

$670
PA1649-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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PA1649
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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