Anti-MEFV Antibody Picoband™

MEFV antibody

Boster Bio Anti-MEFV Antibody Picoband™ catalog # PB9667. Tested in WB applications. This antibody reacts with Human, Rat.

Product Info Summary

SKU: PB9667
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: WB

Customers Who Bought This Also Bought

Product Name

Anti-MEFV Antibody Picoband™

View all MEFV Antibodies

SKU/Catalog Number

PB9667

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-MEFV Antibody Picoband™ catalog # PB9667. Tested in WB applications. This antibody reacts with Human, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MEFV Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9667)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human MEFV, different from the related mouse sequence by eight amino acids, and from the related rat sequence by eleven amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9667 is reactive to MEFV in Human, Rat

Applications

PB9667 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

86 kDa

Calculated molecular weight

86.444kDa

Background of MEFV

MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin). Pyrin is produced in certain white blood cells (neutrophils, eosinophils and monocytes) that play a role in inflammation and in fighting infection. Inside these white blood cells, pyrin is found with thecytoskeleton, the structural framework that helps to define the shape, size, and movement of a cell. Pyrin's protein structure also allows it to interact with other molecules involved in fighting infection and in the inflammatory response. Although pyrin's function is not fully understood, it likely assists in keeping the inflammation process under control. Research indicates that pyrin helps regulate inflammation by interacting with the cytoskeleton. And Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat

Validation Images & Assay Conditions

Gene/Protein Information For MEFV (Source: Uniprot.org, NCBI)

Gene Name

MEFV

Full Name

Pyrin

Weight

86.444kDa

Alternative Names

FMF; FMFmarenostrin; Marenostrin; Mediterranean fever; MEFpyrin; MGC126560; MGC126586; TRIM20 MEFV FMF, MEF, PAAND, TRIM20 MEFV innate immuity regulator, pyrin pyrin|MEFV, pyrin innate immunity regulator|Mediterranean fever|marenostrin

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MEFV, check out the MEFV Infographic

MEFV infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MEFV: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

No publications found for PB9667

*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.

Have you used Anti-MEFV Antibody Picoband™?

Submit a review and receive an Amazon gift card.

  • $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
  • $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit A Review

Be the first to review Anti-MEFV Antibody Picoband™

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

6 Customer Q&As for Anti-MEFV Antibody Picoband™

Question

We appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for placenta using anti-MEFV antibody PB9667. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2020-03-13

Answer

Thanks for the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2020-03-13

Question

Is this PB9667 anti-MEFV antibody reactive to the isotypes of MEFV?

Verified Customer

Verified customer

Asked: 2020-03-05

Answer

The immunogen of PB9667 anti-MEFV antibody is A synthetic peptide corresponding to a sequence at the N-terminus of human MEFV(5-39aa PSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSR), different from the related mouse sequence by eight amino acids, and from the related rat sequence by eleven amino acids. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2020-03-05

Question

My question regarding product PB9667, anti-MEFV antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?

M. Yang

Verified customer

Asked: 2020-02-04

Answer

It is not recommended storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free PB9667 anti-MEFV antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.

Boster Scientific Support

Answered: 2020-02-04

Question

Will PB9667 anti-MEFV antibody work on parafin embedded sections? If so, which fixation method do you recommend we use (PFA, paraformaldehyde, other)?

Verified Customer

Verified customer

Asked: 2019-12-27

Answer

It shows on the product datasheet, PB9667 anti-MEFV antibody as been validated on WB. It is best to use PFA for fixation because it has better tissue penetration ability. PFA needs to be prepared fresh before use. Long term stored PFA turns into formalin, as the PFA molecules congregate and become formalin.

Boster Scientific Support

Answered: 2019-12-27

Question

Is a blocking peptide available for product anti-MEFV antibody (PB9667)?

A. Bhatt

Verified customer

Asked: 2019-06-04

Answer

We do provide the blocking peptide for product anti-MEFV antibody (PB9667). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2019-06-04

Question

We are currently using anti-MEFV antibody PB9667 for rat tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, rat. Is it true that the antibody can work on horse tissues as well?

Verified Customer

Verified customer

Asked: 2019-05-01

Answer

The anti-MEFV antibody (PB9667) has not been tested for cross reactivity specifically with horse tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-05-01

Order DetailsPrice
PB9667

100μg

$370
PB9667-10ug

10μg sample (liquid)

$99
PB9667-Biotin

100 μg Biotin conjugated

$570
PB9667-Cy3

100 μg Cy3 conjugated

$570
PB9667-Dylight488

100 μg Dylight488 conjugated

$570
PB9667-Dylight550

100 μg Dylight550 conjugated

$570
PB9667-Dylight594

100 μg Dylight594 conjugated

$570
PB9667-FITC

100 μg FITC conjugated

$570
PB9667-HRP

100 μg HRP conjugated

$570
PB9667-APC

100 μg APC conjugated

$670
PB9667-PE

100 μg PE conjugated

$670
PB9667-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
Eddy test
In stock
Order Product
PB9667
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.