Anti-PERK EIF2AK3 Monoclonal Antibody

PERK antibody

Boster Bio Anti-PERK EIF2AK3 Monoclonal Antibody catalog # M01992. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Info Summary

SKU: M01992
Size: 100ul
Reactive Species: Human
Host: Mouse
Application: ELISA, WB

Product Name

Anti-PERK EIF2AK3 Monoclonal Antibody

View all PERK Antibodies

SKU/Catalog Number

M01992

Size

100ul

Form

Liquid

Description

Boster Bio Anti-PERK EIF2AK3 Monoclonal Antibody catalog # M01992. Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PERK EIF2AK3 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01992)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

5G5

Isotype

IgG

Immunogen

Purified recombinant fragment of human PERK expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01992 is reactive to EIF2AK3 in Human

Applications

M01992 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

125.216kDa

Background of PERK

Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
ELISA 1:10000

Validation Images & Assay Conditions

Gene/Protein Information For EIF2AK3 (Source: Uniprot.org, NCBI)

Gene Name

EIF2AK3

Full Name

Eukaryotic translation initiation factor 2-alpha kinase 3

Weight

125.216kDa

Superfamily

protein kinase superfamily

Alternative Names

DKFZp781H1925; EC 2.7.11.1; EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3; eukaryotic translation initiation factor 2-alpha kinase 3; hsPEK; PEK; PEKPERKPancreatic eIF2-alpha kinase; PERK; PRKR-like endoplasmic reticulum kinase; WRS EIF2AK3 PEK, PERK, WRS eukaryotic translation initiation factor 2 alpha kinase 3 eukaryotic translation initiation factor 2-alpha kinase 3|PRKR-like endoplasmic reticulum kinase|pancreatic EIF2-alpha kinase|truncated eukaryotic translation initiation factor 2 alpha kinase 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on EIF2AK3, check out the EIF2AK3 Infographic

EIF2AK3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for EIF2AK3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M01992-100ul

100ul

$380

Free Secondary Antibody

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M01992
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$380.00

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