Anti-Cytochrome P450 Reductase/POR Antibody

POR/Cytochrome P450 Reductase antibody

Boster Bio Anti-Cytochrome P450 Reductase/POR Antibody catalog # PA1952. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PA1952
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IHC, ICC, WB

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Product Name

Anti-Cytochrome P450 Reductase/POR Antibody

View all POR/Cytochrome P450 Reductase Antibodies

SKU/Catalog Number

PA1952

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Cytochrome P450 Reductase/POR Antibody catalog # PA1952. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Cytochrome P450 Reductase/POR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1952)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human POR, different from the related rat and mouse sequences by one amino acid.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1952 is reactive to POR in Human, Mouse, Rat

Applications

PA1952 is guaranteed for Flow Cytometry, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

120 kDa

Calculated molecular weight

76.69kDa

Background of POR/Cytochrome P450 Reductase

POR is a membrane-boundenzyme required for electron transfer from NADPH to cytochrome P450 in the endoplasmic reticulum of theeukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Immunocytochemistry, 0.5-1μg/ml, Human
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Flow Cytometry, 1-3μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For POR (Source: Uniprot.org, NCBI)

Gene Name

POR

Full Name

NADPH--cytochrome P450 reductase

Weight

76.69kDa

Superfamily

NADPH--cytochrome P450 reductase family

Alternative Names

CPR; CYPOR; CYPORFLJ26468; Cytochrome P450 Reductase; DKFZp686G04235; EC 1.6.2.4; NADPH--cytochrome P450 reductase; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450R; POR POR CPR, CYPOR, P450R cytochrome p450 oxidoreductase NADPH--cytochrome P450 reductase|NADPH--hemoprotein reductase|NADPH-dependent cytochrome P450 reductase|P450 (cytochrome) oxidoreductase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on POR, check out the POR Infographic

POR infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for POR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
PA1952

100μg

$370
PA1952-10ug

10μg sample (liquid)

$99
PA1952-Biotin

100 μg Biotin conjugated

$570
PA1952-Cy3

100 μg Cy3 conjugated

$570
PA1952-Dylight488

100 μg Dylight488 conjugated

$570
PA1952-Dylight550

100 μg Dylight550 conjugated

$570
PA1952-Dylight594

100 μg Dylight594 conjugated

$570
PA1952-FITC

100 μg FITC conjugated

$570
PA1952-HRP

100 μg HRP conjugated

$570
PA1952-APC

100 μg APC conjugated

$670
PA1952-PE

100 μg PE conjugated

$670
PA1952-carrier-free

Carrier Free

$370

More conjugates/formats

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PA1952
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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