Product Info Summary
SKU: | A04961 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, WB |
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Product info
Product Name
Anti-Retinal dehydrogenase 2 ALDH1A2 Antibody
SKU/Catalog Number
A04961
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Retinal dehydrogenase 2 ALDH1A2 Antibody catalog # A04961. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Retinal dehydrogenase 2 ALDH1A2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04961)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human RIN1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04961 is reactive to ALDH1A2 in Human, Mouse, Rat
Applications
A04961 is guaranteed for IF, IHC, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
56.724kDa
Background of ALDH1A2
Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Colicelli J., Proc. Natl. Acad. Sci. U.S.A. 88:2913-2917(1991).
Han L., Mol. Cell. Biol. 15:1318-1323(1995).
Han L., Proc. Natl. Acad. Sci. U.S.A. 94:4954-4959(1997)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Retinal dehydrogenase 2 ALDH1A2 Antibody A04961
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For ALDH1A2 (Source: Uniprot.org, NCBI)
Gene Name
ALDH1A2
Full Name
Retinal dehydrogenase 2
Weight
56.724kDa
Superfamily
aldehyde dehydrogenase family
Alternative Names
aldehyde dehydrogenase 1 family, member A2; Aldehyde dehydrogenase family 1 member A2; ALDH 1A2; ALDH1A2; EC 1.2.1; EC 1.2.1.36; RALDH 2; RALDH; RALDH(II); RALDH2; RALDH2MGC26444; RALDH2-T; retinal dehydrogenase 2; Retinaldehyde-specific dehydrogenase type 2 ALDH1A2 RALDH(II), RALDH2, RALDH2-T aldehyde dehydrogenase 1 family member A2 retinal dehydrogenase 2|RALDH 2|retinaldehyde-specific dehydrogenase type 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ALDH1A2, check out the ALDH1A2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ALDH1A2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Retinal dehydrogenase 2 ALDH1A2 Antibody (A04961)
Hello CJ!
A04961 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Li Y,Chen F,Chen J,Chan S,He Y,Liu W,Zhang G.Disulfiram/Copper Induces Antitumor Activity against Both Nasopharyngeal Cancer Cells and Cancer-Associated Fibroblasts through ROS/MAPK and Ferroptosis Pathways.Cancers (Basel).2020 Jan 6;12(1):138.doi:10.3390
Species: Human,Mouse
A04961 usage in article: APP:WB, SAMPLE:NPC CELL LINES AND NP69 CELL, DILUTION:1:100
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