Anti-SOCS1 Antibody Picoband®

SOCS-1 antibody

Boster Bio Anti-SOCS1 Antibody Picoband® catalog # A00448. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Info Summary

SKU: A00448
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: IHC, WB

Product Name

Anti-SOCS1 Antibody Picoband®

View all SOCS-1 Antibodies

SKU/Catalog Number

A00448

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-SOCS1 Antibody Picoband® catalog # A00448. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-SOCS1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00448)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human SOCS1, identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00448 is reactive to SOCS1 in Human

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Observed Molecular Weight

27 kDa

Calculated molecular weight

73052 MW

Background of SOCS-1

Suppressor of cytokine signaling 1(SOCS1), also known as Jak-binding protein(JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A00448 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human

Positive Control

WB: human K562 whole cell
IHC: human cervical cancer tissue, human liver cancer tissue, human esophageal squamous carcinoma tissue, human lung cancer tissue, human tonsil tissue

Validation Images & Assay Conditions

Gene/Protein Information For SOCS1 (Source: Uniprot.org, NCBI)

Gene Name

SOCS1

Full Name

Suppressor of cytokine signaling 1

Weight

73052 MW

Superfamily

SOCS1 family

Alternative Names

RAF proto-oncogene serine/threonine-protein kinase;2.7.11.1;Proto-oncogene c-RAF;cRaf;Raf-1;RAF1;RAF; SOCS1 CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP-3, TIP3 suppressor of cytokine signaling 1 suppressor of cytokine signaling 1|JAK binding protein|STAT induced SH3 protein 1|STAT-induced STAT inhibitor 1|Tec-interacting protein 3|cytokine-inducible SH2 protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SOCS1, check out the SOCS1 Infographic

SOCS1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SOCS1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00448

100μg

$370
A00448-10ug

10μg sample (liquid)

$99
A00448-Biotin

100 μg Biotin conjugated

$570
A00448-Cy3

100 μg Cy3 conjugated

$570
A00448-Dylight488

100 μg Dylight488 conjugated

$570
A00448-Dylight550

100 μg Dylight550 conjugated

$570
A00448-Dylight594

100 μg Dylight594 conjugated

$570
A00448-FITC

100 μg FITC conjugated

$570
A00448-HRP

100 μg HRP conjugated

$570
A00448-APC

100 μg APC conjugated

$670
A00448-PE

100 μg PE conjugated

$670
A00448-iFluor647

100 μg iFluor647 conjugated

$670
A00448-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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A00448
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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