Product Info Summary
SKU: | A10501 |
---|---|
Size: | 100ug |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-TMBIM1/Recs1 Antibody
SKU/Catalog Number
A10501
Size
100ug
Form
Liquid (sterile filtered)
Description
Boster Bio Anti-TMBIM1/Recs1 Antibody (Catalog # A10501). Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
Storage & Handling
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Cite This Product
Anti-TMBIM1/Recs1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10501)
Host
Rabbit
Contents
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide
Clonality
Polyclonal
Isotype
IgG
Immunogen
This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the amino terminus of human TMBIM1 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A10501 is reactive to TMBIM1 in Human
Applications
A10501 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
34.607kDa
Background of TMBIM1
This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. TMBIM1 (Transmembrane BAX inhibitor motif-containing protein 1) is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-kB activation. A drosophila homolog of this protein (dNMDA1 with 40% homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ELISA: 1:10,000
IHC: 10µg/mL
WB: 1:500 - 1:2,000
Validation Images & Assay Conditions
Click image to see more details
TMBIM1 was detected in paraffin-embedded sections of human prostate tissues using rabbit anti-TMBIM1 protein A purified polyclonal antibody (Catalog # A10501) at 10 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022).
Click image to see more details
TMBIM1 was detected in paraffin-embedded sections of human tonsil tissues using rabbit anti-TMBIM1 protein A purified polyclonal antibody (Catalog # A10501) at 10 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022).
Click image to see more details
Western blot analysis of TMBIM1 expression in lysates from HeLa cells transfected with pcDNA3-hTMBIM1 (lane 1). No staining is observed in lysates from mock transformed HeLa cells (lane 2). TMBIM1 at 35KD was detected using rabbit anti-TMBIM1 protein A purified polyclonal antibody (Catalog # A10501) at 1:1000. Personal Communication from Srinivasa Srinivasula, CCR-NCI, Bethesda, MD.
Protein Target Info & Infographic
Gene/Protein Information For TMBIM1 (Source: Uniprot.org, NCBI)
Gene Name
TMBIM1
Full Name
Protein lifeguard 3
Weight
34.607kDa
Superfamily
BI1 family
Alternative Names
LFG3; MST100; PP1201; Protein RECS1 homolog; RECS1MSTP100; transmembrane BAX inhibitor motif containing 1; transmembrane BAX inhibitor motif-containing protein 1 TMBIM1 LFG3, MST100, MSTP100, PP1201, RECS1 transmembrane BAX inhibitor motif containing 1 protein lifeguard 3|transmembrane BAX inhibitor motif-containing protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TMBIM1, check out the TMBIM1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TMBIM1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TMBIM1/Recs1 Antibody (A10501)
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