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- Table of Contents
ABCB1 Antibodies
AND ABCB1 ELISA kits, ABCB1 Proteins
Many biological assays use antibodies to detect ABCB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCB1 antibodies...
Designing a Western blot for ABCB1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ABCB1 Western Blot GuideABCB1 Infographic by Boster Bio
All ABCB1 Products
Product
Figures
Specificity
Applications
Price
Anti-ABCB11 Antibody Picoband®
10 Citations
Human, Mouse, Rat
IF, IHC, WB
$370
Cat # PB9414
100 μg/vial
Cat # PB9414
100 μg/vial
Anti-P Glycoprotein/ABCB1 Antibody Picoband®
12 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00049-3
100 μg/vial
Cat # A00049-3
100 μg/vial
Anti-P Glycoprotein/ABCB1 Antibody Picoband®
11 Citations
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # A00049-1
100 μg/vial
Cat # A00049-1
100 μg/vial
Anti-P Glycoprotein/ABCB1 Antibody Picoband®
3 Citations
Human
Flow Cytometry, IF, ICC, WB
$370
Cat # A00049-4
100 μg/vial
Cat # A00049-4
100 μg/vial
Anti-P Glycoprotein/ABCB1 Antibody Picoband®
2 Citations
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00049-5
100 μg/vial
Cat # A00049-5
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # M00049
100 μl
Cat # M00049
100 μl
Human
ELISA, IP, IF, IHC, WB
$146
Cat # M30369-1
20μL, 40μL, 100μL, 200μL
Cat # M30369-1
20μL, 40μL, 100μL, 200μL
Human
Flow Cytometry, IP, IHC-P, IHC-F
$299
Cat # M00049-2
0.1 mg
Cat # M00049-2
0.1 mg
ABCB1 Overview
Facts about ATP-dependent translocase ABCB1.
ATP-dependent translocase ABCB1 (ABCB1)
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ABCB1 |
| Uniprot: | P08183 |
| Entrez: | 5243 |
Family
| Belongs to: |
|---|
| ABC transporter superfamily |
Alternative Names
ABC20; ABCB1; ABCB1B; ATP-binding cassette sub-family B member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; CD243 antigen; CD243; CLCS; colchicin sensitivity; doxorubicin resistance; EC 3.6.3; EC 3.6.3.44; GP170; IBD13; MDR1; MDR1MGC163296; multidrug resistance protein 1; P-glycoprotein 1; P-gp; PGY1; PGY1P-GP
Molecular Weight
Mass (kDA):
141.479 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q21.12 |
| Sequence: | 7; NC_000007.14 (87503017..87713323, complement) |
Tissue Specificity
Expressed in liver, kidney, small intestine and brain.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Apical cell membrane.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Leukemia
- Carcinoma
- Mammary Neoplasms
- Cholangiocarcinoma
- Epilepsy
- Myeloid Leukemia
- Hiv Infections
- Malignant Neoplasm Of Lung
- Nervousness
- Lung Neoplasms
Interacting Proteins
- LAPTM4B
- RNF2
Pathways
- Transport
- Drug Resistance
- Drug Transport
- Excretion
- Localization
- Cell Cycle
- Cell Proliferation
- Secretion
- Methylation
- Pathogenesis
- Rna Interference
- Cell Death
- Intestinal Absorption
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Carboxylation
- Acetylation
- Demethylation
- Glycosylation
- Ubiquitination
- Reduction
Research Areas
- Cancer
- Membrane Trafficking and Chaperones
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCB1
bosterbio.com/bosterbio-gene-info-cards/ABCB1
References
PMID: 2876781 by Chen C.-J., et al. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.
PMID: 1967175 by Chen C.-J., et al. Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins.
51 Publications of Boster ABCB1 Antibodies & ELISA Kits
- PubMed ID: 10.7150/thno.13907, P-glycoprotein Mediates Postoperative Peritoneal Adhesion Formation by Enhancing...
- PubMed ID: 10.3748/wjg.v11.i22.3335, Nude mice multi-drug resistance model of orthotopic transplantation of liver neo...
- PubMed ID: 10.1211/jpp.61.06.0016, Glutathione depletion upregulates P‐glycoprotein expression at the blood‐bra...
- PubMed ID: 10.1158/1541-7786.MCR-18-1072, Breast Cancer Risk–Associated SNPs in the mTOR Promoter Form De Novo KLF5- and...
- PubMed ID: 10.1111/j.1442-2050.2010.01168.x, Various doses of fractioned irradiation modulates multidrug resistance 1 express...
- PubMed ID: 10.1038/srep42465, pH-sensitive micelles for the intracellular co-delivery of curcumin and Pluronic...
- PubMed ID: 10.1021/ac9026127, Design and Implementation of Electrochemical Cytosensor for Evaluation of Cell S...
- PubMed ID: 10.1016/j.phymed.2014.04.029, Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania te...
- PubMed ID: 10.1016/j.jns.2016.02.046, Regulation of P-glycoprotein efflux activity by Z-guggulsterone of Commiphora mu...
- PubMed ID: 10.1016/j.jep.2013.10.028, The mechanism of the opening of the blood–brain barrier by borneol: A pharmaco...
- PubMed ID: 10.1016/j.ijdevneu.2013.10.005, In vitro and in vivo study of dolichyl phosphate on the efflux activity of P-gly...
- PubMed ID: 10.1016/j.bbalip.2021.159006, Hypercholesterolemia risk associated Abca6 does not regulate lipoprotein metabol...
- PubMed ID: 10.1016/j.bbadis.2020.165994, The zonula occludens protein family regulates the hepatic barrier system in the ...
- PubMed ID: 10.1007/s00432-010-0828-5, Expression and significance of hypoxia-inducible factor-1 alpha and MDR1/P-glyco...
- PubMed ID: 10.1002/tox.20391, Growth retardation of fetal rats exposed to nicotine in utero: Possible involvem...
- PubMed ID: 31467112, Chen Q, Deng X,Hu X,Guan S,He M,Wang Y,Wei B,Zhang J,Zhao H,Yao W,Jin F,Liu Y,Ch...
- PubMed ID: 31455288, Sheng X,Li Y,Li Y,Liu W,Lu Z,Zhan J,Xu M,Chen L,Luo X,Cai G,Zhang S.PLOD2 contri...
- PubMed ID: -, Panchamia, Shail. (2020). To Investigate The Impact Of Gut Bacteria On Efflux Tr...
- PubMed ID: -, ACS Appl.Bio Mater.2020,XXXX,XXX,XXX-XXX Publication Date:December 15, 2020 http...
- PubMed ID: 31455288, PLOD2 contributes to drug resistance in laryngeal cancer by promoting cancer ste...
- PubMed ID: 29880886, The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor g...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page