|Application:||IHC, ICC, WB|
Data & Images
|Product Name||Anti-P-GlycoProtein(MDR) Antibody (Monoclonal, F4)|
|Description||Mouse IgG monoclonal antibody for P-Glycoprotein (MDR), ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1 ) detection. Tested with WB, IHC-P, IHC-F, ICC in Human. No cross reactivity with other proteins.|
|Cite This Product||Anti-P-GlycoProtein(MDR) Antibody (Monoclonal, F4) F4 (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1060)|
|Replacement Item||This antibody may replace the following items: sc-13131|sc-1517|sc-1517-R|sc-55510|sc-71557|sc-73354|sc-8313 from Santa Cruz Biotechnology.|
|Application||IHC, ICC, WB
*Our Boster Guarantee covers the use of this product in the above tested applications.
**For positive and negative control design, consult "Tissue specificity" under Protein Target Info.
|Recommended Detection Systems||Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P), IHC(F) and ICC.
*Blocking peptide can be purchased at $50. Contact us for more information
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion for the entire year 2018!
|Immunogen||Mixture of human and hamster drug-resistant whole cells and crude plasma membranes.|
|Cross Reactivity||No cross reactivity with other proteins|
|Contents||Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.|
|Concentration||Add 1ml of PBS buffer will yield a concentration of 100ug/ml.|
|Storage||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
Protein Target Info (Source: Uniprot.org)
You can check the tissue specificity below for information on selecting positive and negative control.
|Protein Name||Multidrug resistance protein 1|
|Molecular Weight||140647 MW|
|Protein Function||Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. .|
|Tissue Specificity||ABCB1: Expressed in liver, kidney, small intestineand brain.|
|Sequence Similarities||Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.|
|Subcellular Localization||Cell membrane; Multi-pass membrane protein.|
|Alternative Names||Multidrug resistance protein 1A;220.127.116.11;ATP-binding cassette sub-family B member 1A;MDR1A;Multidrug resistance protein 3;P-glycoprotein 3;Abcb1a;Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3;|
|Research Areas||signal transduction|metabolism|mitochondrial|pathways and processes|mitochondrial metabolism|mitochondrial markers||