DNTT Antibodies

DNA nucleotidylexotransferase (DNTT)

Template-independent DNA polymerase which catalyzes the random inclusion of deoxynucleoside 5'-triphosphate into the 3'-end of a DNA initiator. One of the in vivo functions of the enzyme is that the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

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Gene Information

Human
Gene Name:	DNTT
Uniprot:	P04053
Entrez:	1791

Family

Belongs to:
DNA polymerase type-X family

Alternative Names

deoxynucleotidyltransferase, terminal; DNTT; EC 2.7.7; EC 2.7.7.31; nucleosidetriphosphate:DNA deoxynucleotidylexotransferase; TdT; TDTDNA nucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; terminal deoxyribonucleotidyltransferase; Terminal transferase

Molecular Weight

Mass (kDA):
58.536 kDA

Genomic Context

Human
Location:	10q24.1
Sequence:	10; NC_000010.11 (96304434..96338564)

Subcellular Localizations

Nucleus.

Diseases

• Leukemia
• Leukemia, Myelocytic, Acute
• Myeloid Leukemia
• Sclerosis
• Cell Transformation, Neoplastic
• Congenital Abnormality
• Leukemia, T-cell
• Multiple Sclerosis
• Nervous System Disorder
• Precursor T-cell Lymphoblastic Leukemia-lymphoma

• Multiple Sclerosis, Relapsing-remitting
• Malignant Neoplasms
• Steroid Sulfatase Deficiency Disease
• Dysmyelopoietic Syndromes

Interacting Proteins

• REL

Pathways

• Methylation
• Gene Silencing
• Pathogenesis
• Transport
• Cell Development
• Dna Methylation
• Histone Modification

• Histone Methylation
• Chromatin Assembly

PTMs

• Methylation

• Deacetylation

Research Areas

• Adaptive Immunity
• Cell Cycle and Replication
• Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DNTT

Boster Bio - Best Uses Of The DNTT Marker

You've heard a lot about the DNTT marker, but what does it do and why should you use it? Here are some useful tips to get you started. Read on for the benefits of this simple tool and a guide to optimizing your experiments. There is a lot of error in experiments, but proper controls can eliminate many of them. Troubleshooting guides can help you figure out the source of your error and eliminate it.

DNTT Marker

The DNTT Marker is a widely used DNA-binding protein. It has been used to detect DNA-binding proteins in a variety of biological processes. Its uses are as diverse as stem cell research, immunology, and virology. Here are just a few of its best uses. To find out more, read on. This article describes how it works and how you can use it to help you improve your research.

Optimization guides

The Boster Bio optimization guides cover flow cytometry, a popular cell biology technique that uses laser-based technology to profile cells in a mixture of heterogeneous fluids. The company offers primers and quick reference guides to explain the basics of the procedure. Additionally, the company offers detailed product datasheets. These can answer your specific questions about the protocols and other technical aspects of the instrument. These guides provide you with the most important information about a given Boster Bio product.