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- Table of Contents
Histone deacetylase 2 Antibodies
AND HDAC2 ELISA kits, Histone deacetylase 2 Proteins
Many biological assays use antibodies to detect Histone deacetylase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone deacetylase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone deacetylase 2 antibodies...
Designing a Western blot for Histone deacetylase 2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HDAC2 Western Blot GuideHDAC2 Infographic by Boster Bio
All HDAC2 Products
Product
Figures
Specificity
Applications
Price
Anti-HDAC2 Antibody Picoband®
3 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00325-3
100 μg/vial
Cat # A00325-3
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # PA1350
100 μg/vial
Cat # PA1350
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00325-1
100 μl
Cat # M00325-1
100 μl
Human, Mouse, Rat
IP, WB
$370
Cat # M00325
100 μl
Cat # M00325
100 μl
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$481
Cat # A00325-1
0.1 mg
Cat # A00325-1
0.1 mg
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00325-3
20μL, 40μL, 100μL, 200μL
Cat # M00325-3
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA
$540
Cat # EKC2422
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2422
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1262
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1262
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat, Primate
ELISA, IF, IHC, WB
$641
Cat # A00325
100ug
Cat # A00325
100ug
SDS-PAGE
$265
Cat # PROTQ92769
Starting from 10ug
Cat # PROTQ92769
Starting from 10ug
HDAC2 Overview
Facts about Histone deacetylase 2.
Histone deacetylase 2 (HDAC2)
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Histone deacetylases act via the formation of large multiprotein complexes. Types transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR.
Gene Information
| Human | |
|---|---|
| Gene Name: | HDAC2 |
| Uniprot: | Q92769 |
| Entrez: | 3066 |
Family
| Belongs to: |
|---|
| histone deacetylase family |
Alternative Names
EC 3.5.1.98; HD2; HDAC2; Histone Deacetylase 2; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1-associated factor 1
Molecular Weight
Mass (kDA):
55.364 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q21 |
| Sequence: | 6; NC_000006.12 (113933028..113971148, complement) |
Tissue Specificity
Widely expressed; lower levels in brain and lung.
Subcellular Localizations
Nucleus. Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Inflammation
- Traditional Serrated Adenoma
- Chronic Obstructive Airway Disease
- Lung Diseases
- Lung Diseases, Obstructive
- Carcinoma
- Asthma
- Malignant Neoplasm Of Breast
- Leukemia
- Mammary Neoplasms
Interacting Proteins
- BCL11B
- BRMS1
- DAXX
- HCFC1
- HDAC1
- MBD1
- MTA1
- MYC
- NPM1
- RFX5
Pathways
- Histone Acetylation
- Cell Cycle
- Methylation
- Chromatin Remodeling
- Histone Deacetylation
- Cell Proliferation
- Dna Methylation
- Pathogenesis
- Localization
- Cell Growth
- Cell Differentiation
- Regulation Of Gene Expression
- Cell Cycle Arrest
PTMs
- Acetylation
- Deacetylation
- Methylation
- Phosphorylation
- Nitrosylation
- Demethylation
- Sumoylation
Research Areas
- Breast Cancer
- Cancer
- Chromatin Research
- Epigenetics
- Phospho-Specific
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HDAC2
bosterbio.com/bosterbio-gene-info-cards/HDAC2
References
PMID: 8917507 by Yang W.-M., et al. Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3.
PMID: 10545197 by Schmidt D.R., et al. Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4.
4 Publications of Boster Histone deacetylase 2 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.biopha.2019.109380, Expression of GR-α and HDAC2 in steroid-Sensitive and steroid-Insensitive inter...
- PubMed ID: 29456664, Wu J, Li X, Qin Y, Cheng J, Hao G, Jin R, Zhu C. Exp Ther Med. 2018 Mar;15(3):26...
- PubMed ID: 25333250, Chen Xm, Xie Xb, Zhao Q, Wang F, Bai Y, Yin Jq, Jiang H, Xie Xl, Jia Q, Huang G....
- PubMed ID: 24265759, Chen Xm, Bai Y, Zhong Yj, Xie Xl, Long Hw, Yang Yy, Wu Sg, Jia Q, Wang Xh. Plos ...
*More publications can be found for each product on its corresponding product page