Anti-Histone deacetylase 2 HDAC2 Antibody

Histone Deacetylase 2/HDAC2 antibody

Boster Bio Anti-Histone deacetylase 2 HDAC2 Antibody (Catalog # A00325-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A00325-1
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

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Product Name

Anti-Histone deacetylase 2 HDAC2 Antibody

View all Histone Deacetylase 2/HDAC2 Antibodies

SKU/Catalog Number

A00325-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Histone deacetylase 2 HDAC2 Antibody (Catalog # A00325-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

HDAC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-Histone deacetylase 2 HDAC2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00325-1)

Host

Rabbit

Contents

HDAC2 antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

HDAC2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human HDAC2. The immunogen is located within the last 50 amino acids of HDAC2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

HDAC2 antibody is human, mouse and rat reactive. At least two isoforms of HDAC2 are known to exist; this antibody will detect both isoforms. HDAC2 antibody is predicted to not cross-react with other members of the HDAC family.

Reactive Species

A00325-1 is reactive to HDAC2 in Human, Mouse, Rat

Applications

A00325-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

55.364kDa

Background of Histone Deacetylase 2/HDAC2

The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class I of the HDAC family comprises four members, HDAC1, 2, 3, and 8, each of which contains a deacetylase domain and exhibits a different, individual substrate specificity and function in vivo (1). HDAC2 was first identified as as a mammalian homolog to the yeast transcriptional regulator RPD3 (2). HDAC2 forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor (2,3). Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events (4).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

HDAC2 antibody can be used for detection of HDAC2 by Western blot at 0.5 - 1 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For HDAC2 (Source: Uniprot.org, NCBI)

Gene Name

HDAC2

Full Name

Histone deacetylase 2

Weight

55.364kDa

Superfamily

histone deacetylase family

Alternative Names

EC 3.5.1.98; HD2; HDAC2; Histone Deacetylase 2; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1-associated factor 1 HDAC2 HD2, KDAC2, RPD3, YAF1 histone deacetylase 2 histone deacetylase 2|YY1-associated factor 1|transcriptional regulator homolog RPD3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on HDAC2, check out the HDAC2 Infographic

HDAC2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HDAC2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00325-1-0.1 mg

0.1 mg

$449

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