Anti-HDAC-2 (C-terminus) Antibody

Histone Deacetylase 2/HDAC2 antibody

Boster Bio Anti-HDAC-2 (C-terminus) Antibody catalog # A00325. Tested in IF applications. This antibody reacts with Human, Mouse, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: A00325
Size: 100ug
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF

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Product Name

Anti-HDAC-2 (C-terminus) Antibody

View all Histone Deacetylase 2/HDAC2 Antibodies

SKU/Catalog Number

A00325

Size

100ug

Form

Liquid

Description

Boster Bio Anti-HDAC-2 (C-terminus) Antibody catalog # A00325. Tested in IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Cite This Product

Anti-HDAC-2 (C-terminus) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00325)

Host

Rabbit

Clonality

Polyclonal

Cross Reactivity

No cross reactivity with other proteins.

Reactive Species

A00325 is reactive to HDAC2 in Human, Mouse, Rat

Applications

A00325 is guaranteed for IF Boster Guarantee

Background of Histone Deacetylase 2/HDAC2

Histone deacetylase 2 is an enzyme that in humans is encoded by the HDAC2 gene. This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Betz et al. (1998) performed PCR using HDAC2-specific primers to screen a somatic cell hybrid mapping panel. They mapped the HDAC2 gene to human chromosome 6q21, a region of the genome altered in some cancers, including retinoblastoma.

Antibody Validation

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western Blot, 1μg/ml, human, mouse, rat, Primate
Direct ELISA, 1:20, 000 - 1:60, 000, human, mouse, rat, Primate
Immunohistochemistry: 1:100-1:500, human, mouse, rat, Primate
IF Microscopy: 1:100-1:500, human, mouse, rat, Primate

Validation Images & Assay Conditions

Gene/Protein Information For HDAC2 (Source: Uniprot.org, NCBI)

Uniprot ID

Q92769

Gene ID

3066

Gene Name

HDAC2

Full Name

Histone deacetylase 2

Weight

55.364kDa

Superfamily

histone deacetylase family

Alternative Names

EC 3.5.1.98; HD2; HDAC2; Histone Deacetylase 2; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1-associated factor 1 HDAC2 HD2, KDAC2, RPD3, YAF1 histone deacetylase 2 histone deacetylase 2|YY1-associated factor 1|transcriptional regulator homolog RPD3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on HDAC2, check out the HDAC2 Infographic

HDAC2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HDAC2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

A00325 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Chen Xm, Xie Xb, Zhao Q, Wang F, Bai Y, Yin Jq, Jiang H, Xie Xl, Jia Q, Huang G. Mol Med Rep. 2015 Jan;11(1):105-12. Doi: 10.3892/Mmr.2014.2733. Epub 2014 Oct 21. Ampelopsin Induces Apoptosis By Regulating Multiple C-Myc/S-Phase Kinase-Associated ...

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SKU:A00325

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A00325
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$487.00

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