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- Table of Contents
Interleukin-21 Antibodies
AND IL21 ELISA kits, Interleukin-21 Proteins
Many biological assays use antibodies to detect Interleukin-21, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Interleukin-21 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Interleukin-21 antibodies...
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IL21 Infographic by Boster Bio
All IL21 Products
Product
Figures
Specificity
Applications
Price
Mouse IL-21/Interleukin-21 ELISA Kit PicoKine®
15 Citations 7 Q&As
Mouse
ELISA
$499
Cat # EK0797
96 wells/kit, with removable strips.
Cat # EK0797
96 wells/kit, with removable strips.
Human
Cell Culture
$77
Cat # PROTQ9HBE4-5
5ug,20ug,100ug
Cat # PROTQ9HBE4-5
5ug,20ug,100ug
Mouse
Cell Culture
$77
Cat # PROTQ9ES17-3
5ug,20ug,100ug
Cat # PROTQ9ES17-3
5ug,20ug,100ug
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00459
100 μg
Cat # M00459
100 μg
Cynomolgus monkey, Human, Mouse, Rabbit, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00459-1
100 μg
Cat # M00459-1
100 μg
IL21 Overview
Facts about Interleukin-21.
Interleukin-21 (IL21)
May encourage the transition between innate and adaptive immunity. Induces the creation of IgG(1) and IgG(3) in B-cells (By similarity).
May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli.
Gene Information
| Human | |
|---|---|
| Gene Name: | IL21 |
| Uniprot: | Q9HBE4 |
| Entrez: | 59067 |
Family
| Belongs to: |
|---|
| IL-15/IL-21 family |
Alternative Names
CVID11; IL21; IL-21; IL-21Za11interleukin-21; interleukin 21; interleukin-21 isoform; Za11
Molecular Weight
Mass (kDA):
18.653 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q27 |
| Sequence: | 4; NC_000004.12 (122610108..122621066, complement) |
Tissue Specificity
Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes.
Subcellular Localizations
Secreted.
Diseases
- Autoimmune Reaction
- Autoimmune Diseases
- Celiac Disease
- Arthritis
- Diabetes Mellitus
- Diabetes Mellitus, Insulin-dependent
- Rheumatoid Arthritis
- Dysequilibrium Syndrome
- Lupus Erythematosus, Systemic
- Ulcer
- Neoplasms
- Colitis
- Autoimmunity
Pathways
- Pathogenesis
- Cell Differentiation
- Cell Activation
- Secretion
- Immunoglobulin Production
- B Cell Differentiation
- T Cell Activation
- Immune Response
- Cell Development
- Cytokine Production
- Germinal Center Formation
- Cytokine Secretion
- Plasma Cell Differentiation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IL21
bosterbio.com/bosterbio-gene-info-cards/IL21
References
PMID: 11081504 by Parrish-Novak J., et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.
PMID: 17673207 by Rahman M., et al. Cloning and characterization of an isoform of interleukin-21.
15 Publications of Boster Interleukin-21 Antibodies & ELISA Kits
- PubMed ID: 10.7150/thno.44715, Characterization of IL-21-expressing recombinant hepatitis B virus (HBV) as a th...
- PubMed ID: 10.7150/thno.35331, IL-21-based therapies induce clearance of hepatitis B virus persistence in mouse...
- PubMed ID: 10.1097/MEG.0000000000001712, Upregulation of microRNA-219-5p relieves ulcerative colitis through balancing th...
- PubMed ID: 10.1039/D1FO00596K, A polysaccharide from natural Cordyceps sinensis regulates the intestinal immuni...
- PubMed ID: 10.1038/srep29556, Live attenuated Salmonella displaying HIV-1 10E8 epitope on fimbriae: systemic a...
- PubMed ID: 10.1021/acs.jafc.5b06177, Lactobacillus plantarum NCU116 Attenuates Cyclophosphamide-Induced Immunosuppres...
- PubMed ID: 10.1016/j.fct.2020.111244, Ganoderma atrum polysaccharide ameliorates intestinal mucosal dysfunction associ...
- PubMed ID: 10.1016/j.carbpol.2020.115957, Cultured Cordyceps sinensis polysaccharides modulate intestinal mucosal immunity...
- PubMed ID: 10.1016/j.biopha.2018.03.066, The effectiveness of cyclooxygenase-2 inhibitors and evaluation of angiogenesis ...
- PubMed ID: 10.1016/j.antiviral.2021.105076, Prior transient exposure to interleukin-21 delivered by recombinant adeno-associ...
- PubMed ID: , Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of v...
- PubMed ID: 33865876, Shen Z,Gao Z,Gu C,Wu J,Wang J,Zhang J,Xie Y,Liu J.Prior transient exposure to in...
- PubMed ID: 27411313, Live attenuated Salmonella displaying HIV-1 10E8 epitope on fimbriae: systemic a...
- PubMed ID: 29242561, Shen, Z., Yang, H., Yang, S., Wang, W., Cui, X., Zhou, X.,..., & Liu, J. (2017)....
- PubMed ID: 25546013, Yu Ht, Tian D, Wang Jy, Guo Cx, Li Y, Wang X, Li D, Zhang Fm, Zhuang M, Ling H. ...
*More publications can be found for each product on its corresponding product page