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- Table of Contents
NOS1 Antibodies
AND NOS1 ELISA kits, NOS1 Proteins
Many biological assays use antibodies to detect NOS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NOS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NOS1 antibodies...
Designing a Western blot for NOS1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the NOS1 Western Blot GuideDesigning an IHC experiment for NOS1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NOS1 IHC GuideNOS1 Infographic by Boster Bio
All NOS1 Products
Product
Figures
Specificity
Applications
Price
Anti-nNOS (neuronal)/NOS1 Antibody Picoband®
4 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01070-2
100 μg/vial
Cat # A01070-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03060-3
100 μg/vial
Cat # A03060-3
100 μg/vial
Anti-nNOS (neuronal)/NOS1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
WB
$370
Cat # A01070
100 μg/vial
Cat # A01070
100 μg/vial
Human, Mouse, Rat
ELISA
$540
Cat # EKC2094
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2094
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1406
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1406
1 kit, containing one 96-well plate and all necessary reagents
NOS1 Overview
Facts about Nitric oxide synthase, brain.
Nitric oxide synthase, brain (NOS1)
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter.
Probably has nitrosylase action and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NOS1 |
| Uniprot: | P29475 |
| Entrez: | 4842 |
Family
| Belongs to: |
|---|
| NOS family |
Alternative Names
bNOS; brain; Constitutive NOS; EC 1.14.13.39; IHPS1; Neuronal NOS; nitric oxide synthase 1 (neuronal); nNOS; N-NOS; nNOSNOS type I; NOS; NOS1; Peptidyl-cysteine S-nitrosylase NOS1
Molecular Weight
Mass (kDA):
160.97 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q24.22 |
| Sequence: | 12; NC_000012.12 (117208142..117361802, complement) |
Tissue Specificity
Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland.
Subcellular Localizations
Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine. In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity).
Diseases
- Nervousness
- Hypertensive Disease
- Ischemia
- Inflammation
- Neurotoxicity Syndromes
- Diabetes Mellitus
- Disease Of Adrenal Medulla
- Pain
- Hypoxia
- Nerve Degeneration
- Diabetes Mellitus, Experimental
- Macule
Interacting Proteins
- VAC14
Pathways
- Localization
- Pathogenesis
- Cell Death
- Secretion
- Aging
- Excretion
- Innervation
- Neuroprotection
- Vasodilation
- Transport
- Glomerular Filtration
- Reflex
- Tubuloglomerular Feedback
PTMs
- Phosphorylation
- Nitration
- Oxidation
- Reduction
- Nitrosylation
- Cleavage
- Dephosphorylation
- Ubiquitination
- Methylation
Research Areas
- Asthma
- Cancer
- HIF Target Genes
- Hypoxia
- Immunology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOS1
bosterbio.com/bosterbio-gene-info-cards/NOS1
References
PMID: 7528745 by Hall A.V., et al. Structural organization of the human neuronal nitric oxide synthase gene (NOS1).
PMID: 7515942 by Fujisawa H., et al. Expression of two types of nitric oxide synthase mRNA in human neuroblastoma cell lines.
19 Publications of Boster NOS1 Antibodies & ELISA Kits
- PubMed ID: 10.1089/adt.2018.912, Protective and Modulatory Effects of Trapa bispinosa and Trigonella foenum-graec...
- PubMed ID: 10.1007/s11596-018-1904-3, Effects of Repetitive Transcranial Magnetic Stimulation on Astrocytes Proliferat...
- PubMed ID: 31742429, Singh S,Kumar V,Kumar N,Sharma P,Waheed SM.Protective and Modulatory Effects of ...
- PubMed ID: 29581524, George AK, Behera J, Kelly KE, Mondal NK, Richardson KP, Tyagi N. Sci Rep. 2018 ...
- PubMed ID: 29207043, Naringenin induces laxative effects by upregulating the expression levels of c-K...
- PubMed ID: 12046087, Distribution of constitutive nitric oxide synthase in the jejunum of adult rat
- PubMed ID: 28218896, Ding J, Tang Y, Tang Z, Zhang X, Wang G. Med Sci Monit. 2017 Feb 20;23:929-937. ...
- PubMed ID: 25797533, Kong L, Wei Q, Fedail Js, Shi F, Nagaoka K, Watanabe G. J Reprod Dev. 2015;61(3)...
- PubMed ID: 25280359, Liu R, Li Yp, Zhang Wg, Fu Qq, Liu N, Zhou Gh. Meat Sci. 2015 Jan;99:25-31. Doi:...
- PubMed ID: 25183664, Xu M, Wei Q, Zheng K, Mao D, Zheng Y, Li Y, Shi F. Acta Histochem. 2014 Oct;116(...
- PubMed ID: 21194187, Zhang W, Wei Qw, Wang Zc, Ding W, Wang W, Shi Fx. J Zhejiang Univ Sci B. 2011 Ja...
- PubMed ID: 24238988, Li Y, Zhou X, Wei Qw, Huang Rh, Shi Fx. Acta Histochem. 2014 Apr;116(3):466-73. ...
- PubMed ID: 17417610, Wu R, Yin J, Yao K, Haefliger I. Mol Vis. 2007 Apr 2;13:493-6. Inhibition By Bri...
- PubMed ID: 22498451, Ding W, Zhang W, Hui Fm, Zhang Yh, Zhang Ff, Li Xm, Shi Fx. Anim Reprod Sci. 201...
- PubMed ID: 25726374, Zheng K, Sulieman Fj, Li J, Wei Q, Xu M, Shi F. Reprod Biol. 2015 Mar;15(1):27-3...
- PubMed ID: 24254997, Fedail Js, Zheng K, Wei Q, Kong L, Shi F. Endocrine. 2014 Aug;46(3):594-604. Doi...
- PubMed ID: 15081376, Yuan Zr, Liu B, Zhang Y, Yuan L, Muteliefu G, Lu J. Brain Res. 2004 May 15;1008(...
- PubMed ID: 19931630, Wang J, Yan L, Zhao X, Wu W, Zhou Lh. Nitric Oxide. 2010 Jan 1;22(1):37-42. Doi:...
- PubMed ID: 23226517, Chang Mj, Xiao Jh, Wang Y, Yan Yl, Yang J, Wang Jl. Plos One. 2012;7(12):E50291....
*More publications can be found for each product on its corresponding product page