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Required for the CCR4-NOT complicated structural integrity. Can repress transcription and may link the CCR4-NOT complicated to transcriptional regulation; the repressive function may specifically involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2.
|Sequence:||12; NC_000012.12 (70242993..70355257)|
Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes.