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- Table of Contents
PTGS2 Antibodies
AND PTGS2 ELISA kits, PTGS2 Proteins
Many biological assays use antibodies to detect PTGS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTGS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTGS2 antibodies...
Designing a Western blot for PTGS2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PTGS2 Western Blot GuidePTGS2 Infographic by Boster Bio
All PTGS2 Products
Product
Figures
Specificity
Applications
Price
Anti-MyD88 Antibody Picoband®
23 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB, ELISA (Cap)
$370
Cat # PB9148
100 μg/vial
Cat # PB9148
100 μg/vial
Anti-COX2/Cyclooxygenase 2/PTGS2 Antibody Picoband®
41 Citations
Human, Mouse
IHC, WB
$370
Cat # PA1725
100 μg/vial
Cat # PA1725
100 μg/vial
Anti-COX2/Cyclooxygenase 2/PTGS2 Picoband® Antibody
13 Citations
Human, Mouse
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00084-2
100 μg/vial
Cat # A00084-2
100 μg/vial
Anti-COX2 PTGS2 Rabbit Monoclonal Antibody
16 Citations
Human, Mouse
IF, ICC, WB
$370
Cat # M00084
100 μl
Cat # M00084
100 μl
Anti-COX2/Cyclooxygenase 2/PTGS2 Antibody Picoband®
15 Citations
Human
WB
$370
Cat # A00084
100 μg/vial
Cat # A00084
100 μg/vial
Human/Mouse COX-2 ELISA Kit PicoKine®
1 Citations
Human, Mouse
ELISA
$750
Cat # EK2289
96 wells/kit, with removable strips.
Cat # EK2289
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, IF, IHC, WB
$146
Cat # M00084-6
20μL, 40μL, 100μL, 200μL
Cat # M00084-6
20μL, 40μL, 100μL, 200μL
PTGS2 Overview
Facts about Prostaglandin G/H synthase 2.
Prostaglandin G/H synthase 2 (PTGS2)
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis (PubMed:26859324, PubMed:27226593). Constitutively expressed in certain tissues in physiological conditions, like the endothelium, kidney and brain, and in pathological conditions, such as in cancer.
PTGS2 accounts for production of inflammatory prostaglandins. Up- regulation of PTGS2 is also correlated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis.
Gene Information
| Human | |
|---|---|
| Gene Name: | PTGS2 |
| Uniprot: | P35354 |
| Entrez: | 5743 |
Family
| Belongs to: |
|---|
| prostaglandin G/H synthase family |
Alternative Names
COX2; COX-2; COX2cyclooxygenase 2b; cyclooxygenase-2; EC 1.14.99; EC 1.14.99.1; GRIPGHS; hCox-2; PGG/HS; PGH synthase 2; PGHS-2; PHS II; PHS-2; PHS-II; prostaglandin G/H synthase 2; prostaglandin G/H synthase and cyclooxygenase; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase andcyclooxygenase); Prostaglandin-endoperoxide synthase 2; PTGS2
Molecular Weight
Mass (kDA):
68.996 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q31.1 |
| Sequence: | 1; NC_000001.11 (186671791..186680423, complement) |
Subcellular Localizations
Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Inflammation
- Carcinoma
- Carcinogenesis
- Tumor Angiogenesis
- Adenocarcinoma
- Pain
- Colorectal Cancer
- Neoplasm Metastasis
- Arthritis
- Malignant Tumor Of Colon
- Cell Transformation, Neoplastic
Pathways
- Angiogenesis
- Cell Proliferation
- Pathogenesis
- Cell Growth
- Inflammatory Response
- Secretion
- Cell Cycle
- Cell Death
- Localization
- Induction Of Apoptosis
- Immune Response
- Methylation
- Platelet Aggregation
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Acetylation
- Oxidation
- Reduction
- Nitration
- Demethylation
- Ubiquitination
- Dephosphorylation
Research Areas
- Cancer
- Cell Biology
- Cellular Markers
- Cytokine Research
- Hypoxia
- Lipid and Metabolism
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTGS2
bosterbio.com/bosterbio-gene-info-cards/PTGS2
References
PMID: 8473346 by Jones D.A., et al. Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines.
PMID: 1380156 by Hla T., et al. Human cyclooxygenase-2 cDNA.
46 Publications of Boster PTGS2 Antibodies & ELISA Kits
- PubMed ID: PMID:29218088, Effect of astragaloside IV on diabetic gastric mucosa in vivo and in vitro
- PubMed ID: 10.4103/1673-5374.147934, Puerarin protects brain tissue against cerebral ischemia/reperfusion injury by i...
- PubMed ID: 10.3389/fphar.2021.798421, Gastroprotective Effects of Periplaneta americana L. Extract Against Etha...
- PubMed ID: 10.1016/j.phymed.2021.153813, The Bioactive Alkaloids Identified from Cortex Phellodendri Ameliorate Benign Pr...
- PubMed ID: 10.1016/j.intimp.2021.108119, Nootkatone protects cartilage against degeneration in mice by inhibiting NF-κB ...
- PubMed ID: 31091873, Zhang ZC,Zhou Q,Yang Y,Wang Y,Zhang JL.Highly Acylated Anthocyanins from Purple ...
- PubMed ID: 32523341, Yuan L,Li Q,Bai D,Shang X,Hu F,Chen Z,An T,Chen Y,Zhang X.La2O3 Nanoparticles In...
- PubMed ID: 32640491, Li X,Liang X,Li S,Qi X,Du N,Yang D. Effect of environmental tobacco smoke on COX...
- PubMed ID: 31882548, Zhu, G., Lin, C., Cheng, Z., Wang, Q., Hoffman, R. M., Singh, S. R., ... & Ye, J...
- PubMed ID: 30276528, Chitosan/hyaluronic acid/plasmid-DNA nanoparticles encoding interleukin-1 recept...
- PubMed ID: 27895584, Induced pluripotent stem cells inhibit bleomycin-induced pulmonary fibrosis in m...
- PubMed ID: 28553282, Co-Inflammatory Roles of TGF%u03B21 in the Presence of TNF%u03B1 Drive a Pro-inf...
- PubMed ID: 30150280, Combination of fasudil and celecoxib promotes the recovery of injured spinal cor...
- PubMed ID: 29442011, Puerarin protects brain tissue against cerebral ischemia/reperfusion injury by i...
- PubMed ID: 29393449, Effect of cyclooxygenase-2 inhibition on the development of post-traumatic stres...
- PubMed ID: 26617722, MicroRNA-101 regulates the viability and invasion of cervical cancer cells
- PubMed ID: 26257474, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Downregulates the Expr...
- PubMed ID: 28123497, Odontogenic epithelial proliferation is correlated with COX-2 expression in dent...
- PubMed ID: 27562754, Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precan...
- PubMed ID: 27297132, miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PG...
- PubMed ID: 26904148, Glycyrrhizic Acid Attenuates Sepsis-Induced Acute Kidney Injury by Inhibiting NF...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page