PTGS2 Antibodies

AND PTGS2 ELISA kits, PTGS2 Proteins

Many biological assays use antibodies to detect PTGS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTGS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTGS2 antibodies...

We validate the specificity of these antibodies to PTGS2 by testing them on tissues known to express PTGS2 positively and negatively. Browse below to find the PTGS2 antibody that suites your experiment. We have 12 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTGS2 Infographic by Boster Bio

All PTGS2 Products

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Product

Figures

Specificity

Applications

Price

Anti-MyD88 Antibody Picoband®

21 Citations 5 Q&As

Western blot analysis of MyD88 using anti-MyD88 antibody (PB9148)

IF analysis of MYD88 using anti-MYD88 antibody (PB9148) MYD88 was detected in paraffin-embedded section of human mammary cancar tissues

IHC analysis of MYD88 using anti-MYD88 antibody (PB9148)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, IHC-F, ICC, WB, ELISA (Cap)

$370
Cat # PB9148
100 μg/vial

Anti-COX2/Cyclooxygenase 2/PTGS2 Antibody Picoband®

39 Citations 1 Q&As

Western blot analysis of PTGS2 using anti-PTGS2 antibody (PA1725)

IHC analysis of SOX2 using anti-SOX2 antibody (PA1725)

Human, Mouse

IHC, WB

$370
Cat # PA1725
100 μg/vial

Anti-COX2/Cyclooxygenase 2/PTGS2 Antibody Picoband®

14 Citations

The pretreatment of RD-6 inhibited the IL-17 signaling pathway in indomethacin-induced GU rats

Western blot analysis of PTGS2 using anti-PTGS2 antibody (A00084)

Human

$370
Cat # A00084
100 μg/vial

Anti-COX2 PTGS2 Rabbit Monoclonal Antibody

15 Citations

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature

Western blot analysis of COX2 expression in RAW264

Immunofluorescent analysis using the Antibody at 1:150 dilution

Human, Mouse

IF, ICC, WB

$370
Cat # M00084
100 μl

Anti-Cox-2 Antibody

3 Citations

Boster's anti-Cox2 is shown to detect Cox-2 present in Cox-2 transfected Sf9 cell extract (lane 1) and IL-1ß induced WISH cell extract (lane 2)

Human, Mouse, Rat

ELISA, IHC, WB

$578
Cat # A00084-1
100uL

Anti-Cox2 PTGS2 Monoclonal Antibody

1 Citations

All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature

Western blot analysis of Cox2 expression in A549 cell lysate

Human, Mouse

IP, IHC, WB

$370
Cat # M00084-1
100 μl

Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348

Western Blotting resultWestern Blot of HeLa cell lysate using anti-COX-2 rabbit monoclonal antibody (Clone RM348) at a 1:20000 dilution

Human

IHC, WB

$449
Cat # M00084-2
100uL

Anti-COX2/Cyclooxygenase 2/PTGS2 Picoband® Antibody

11 Citations

Western blot analysis of PTGS2 using anti-PTGS2 antibody (A00084-2)

IHC analysis of PTGS2 using anti-PTGS2 antibody (A00084-2)

Effects of maltol on the levels of inflammation cytokines in cisplatin-induced renal toxicity

Human, Mouse

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A00084-2
100 μg/vial

Anti-Cox-2 (T594) PTGS2 Antibody

Western blot (WB) analysis of Cox-2 (T594) polyclonal antibody at 1:500 dilution
Lane1:CT26 whole cell lysate(20ug)
Lane2:PC12 whole cell lysate(40ug)
Lane3:Hela whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Cox-2 (T594) pAb in paraffin-embedded human breast carcinoma tissue at 1:100

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A00084T594
100ul

Anti-PTGS2 Antibody

Human

$299
Cat # M00084-4
50 µl

Human/Mouse COX-2 ELISA Kit PicoKine®

1 Citations

Human, Mouse

ELISA

$750
Cat # EK2289
96 wells/kit, with removable strips.

Anti-COX2 Rabbit Monoclonal Antibody

Human appendix was stained with anti-COX2 rabbit antibody

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-COX2 antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$146
Cat # M00084-6
20μL, 40μL, 100μL, 200μL

PTGS2 Overview

Facts about Prostaglandin G/H synthase 2.

PTGS2 3D structure. Source: alphafold

Prostaglandin G/H synthase 2 (PTGS2)

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis (PubMed:26859324, PubMed:27226593). Constitutively expressed in certain tissues in physiological conditions, like the endothelium, kidney and brain, and in pathological conditions, such as in cancer.

PTGS2 accounts for production of inflammatory prostaglandins. Up- regulation of PTGS2 is also correlated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis.

Gene Information

Human
Gene Name:	PTGS2
Uniprot:	P35354
Entrez:	5743

Family

Belongs to:

prostaglandin G/H synthase family

Alternative Names

COX2; COX-2; COX2cyclooxygenase 2b; cyclooxygenase-2; EC 1.14.99; EC 1.14.99.1; GRIPGHS; hCox-2; PGG/HS; PGH synthase 2; PGHS-2; PHS II; PHS-2; PHS-II; prostaglandin G/H synthase 2; prostaglandin G/H synthase and cyclooxygenase; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase andcyclooxygenase); Prostaglandin-endoperoxide synthase 2; PTGS2

Molecular Weight

Mass (kDA):
68.996 kDA

Genomic Context


Human

Location:	1q31.1
Sequence:	1; NC_000001.11 (186671791..186680423, complement)

Subcellular Localizations

Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Inflammation
Carcinoma
Carcinogenesis
Tumor Angiogenesis
Adenocarcinoma
Pain
Colorectal Cancer
Neoplasm Metastasis
Arthritis
Malignant Tumor Of Colon
Cell Transformation, Neoplastic

Colorectal Neoplasms
Colonic Neoplasms
Rheumatoid Arthritis
Degenerative Polyarthritis
Pathologic Neovascularization
Cell Invasion
Malignant Squamous Cell Neoplasm

Pathways

Angiogenesis
Cell Proliferation
Pathogenesis
Cell Growth
Inflammatory Response
Secretion
Cell Cycle
Cell Death
Localization
Induction Of Apoptosis
Immune Response
Methylation
Platelet Aggregation

Parturition
Excretion
Ovulation
Reverse Transcription
Cell Migration
Cytokine Production
Cell Adhesion

PTMs

Phosphorylation
Cleavage
Methylation
Acetylation
Oxidation
Reduction
Nitration
Demethylation
Ubiquitination
Dephosphorylation

Glycosylation
Carboxylation
Deacetylation
Hydroxylation
Amidation
Biotinylation
Prenylation
Acylation
Phosphorothioation
Farnesylation

Research Areas

Cancer
Cell Biology
Cellular Markers
Cytokine Research
Hypoxia

Lipid and Metabolism
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTGS2

References

PMID: 8473346 by Jones D.A., et al. Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines.

PMID: 1380156 by Hla T., et al. Human cyclooxygenase-2 cDNA.

46 Publications of Boster PTGS2 Antibodies & ELISA Kits

PubMed ID: PMID:29218088, Effect of astragaloside IV on diabetic gastric mucosa in vivo and in vitro
PubMed ID: 10.4103/1673-5374.147934, Puerarin protects brain tissue against cerebral ischemia/reperfusion injury by i...
PubMed ID: 10.3389/fphar.2021.798421, Gastroprotective Effects of Periplaneta americana L. Extract Against Etha...
PubMed ID: 10.1016/j.phymed.2021.153813, The Bioactive Alkaloids Identified from Cortex Phellodendri Ameliorate Benign Pr...
PubMed ID: 10.1016/j.intimp.2021.108119, Nootkatone protects cartilage against degeneration in mice by inhibiting NF-κB ...
PubMed ID: 31091873, Zhang ZC,Zhou Q,Yang Y,Wang Y,Zhang JL.Highly Acylated Anthocyanins from Purple ...
PubMed ID: 32523341, Yuan L,Li Q,Bai D,Shang X,Hu F,Chen Z,An T,Chen Y,Zhang X.La2O3 Nanoparticles In...
PubMed ID: 32640491, Li X,Liang X,Li S,Qi X,Du N,Yang D. Effect of environmental tobacco smoke on COX...
PubMed ID: 31882548, Zhu, G., Lin, C., Cheng, Z., Wang, Q., Hoffman, R. M., Singh, S. R., ... & Ye, J...
PubMed ID: 30276528, Chitosan/hyaluronic acid/plasmid-DNA nanoparticles encoding interleukin-1 recept...
PubMed ID: 27895584, Induced pluripotent stem cells inhibit bleomycin-induced pulmonary fibrosis in m...
PubMed ID: 28553282, Co-Inflammatory Roles of TGF%u03B21 in the Presence of TNF%u03B1 Drive a Pro-inf...
PubMed ID: 30150280, Combination of fasudil and celecoxib promotes the recovery of injured spinal cor...
PubMed ID: 29442011, Puerarin protects brain tissue against cerebral ischemia/reperfusion injury by i...
PubMed ID: 29393449, Effect of cyclooxygenase-2 inhibition on the development of post-traumatic stres...
PubMed ID: 26617722, MicroRNA-101 regulates the viability and invasion of cervical cancer cells
PubMed ID: 26257474, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Downregulates the Expr...
PubMed ID: 28123497, Odontogenic epithelial proliferation is correlated with COX-2 expression in dent...
PubMed ID: 27562754, Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precan...
PubMed ID: 27297132, miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PG...
PubMed ID: 26904148, Glycyrrhizic Acid Attenuates Sepsis-Induced Acute Kidney Injury by Inhibiting NF...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page