Anti-COX2/Cyclooxygenase 2/PTGS2 Picoband™ Antibody

COX-2 antibody

Boster Bio Anti-COX2/Cyclooxygenase 2/PTGS2 Picoband™ Antibody catalog # A00084-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A00084-2
Size: 100 μg/vial
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, Flow Cytometry, WB

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Product Name

Anti-COX2/Cyclooxygenase 2/PTGS2 Picoband™ Antibody

View all COX-2 Antibodies

SKU/Catalog Number

A00084-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-COX2/Cyclooxygenase 2/PTGS2 Picoband™ Antibody catalog # A00084-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-COX2/Cyclooxygenase 2/PTGS2 Picoband™ Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00084-2)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human COX2/Cyclooxygenase 2/PTGS2 recombinant protein (Position: A18-L604).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins.

Reactive Species

A00084-2 is reactive to PTGS2 in Human, Mouse

Applications

A00084-2 is guaranteed for ELISA, Flow Cytometry, WB Boster Guarantee

Background of COX-2

Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. It is mapped to 1q31.1. Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.25μg/ml, Human, Mouse
Flow Cytometry, 1-3μg/1x106 cells, Human
Direct ELISA, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For PTGS2 (Source: Uniprot.org, NCBI)

Uniprot ID

P35354

Gene ID

5743

Gene Name

PTGS2

Full Name

Prostaglandin G/H synthase 2

Weight

68.996kDa

Superfamily

prostaglandin G/H synthase family

Alternative Names

COX2; COX-2; COX2cyclooxygenase 2b; cyclooxygenase-2; EC 1.14.99; EC 1.14.99.1; GRIPGHS; hCox-2; PGG/HS; PGH synthase 2; PGHS-2; PHS II; PHS-2; PHS-II; prostaglandin G/H synthase 2; prostaglandin G/H synthase and cyclooxygenase; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase andcyclooxygenase); Prostaglandin-endoperoxide synthase 2; PTGS2 PTGS2 COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 prostaglandin G/H synthase 2|PGH synthase 2|PHS II|cyclooxygenase 2|cyclooxygenase 2b|prostaglandin H2 synthase 2|prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PTGS2, check out the PTGS2 Infographic

PTGS2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PTGS2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Total: $315

SKU:A00084-2

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A00084-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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