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Product Info Summary
| SKU: | M00084-4 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | WB |
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Product info
Product Name
Anti-PTGS2 Antibody
SKU/Catalog Number
M00084-4
Size
50 µl
Description
Boster Bio Anti-PTGS2 Antibody (Catalog # M00084-4). Tested in WB application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-PTGS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00084-4)
Host
Mouse
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Monoclonal
Clone Number
2104CT1721.122.37
Isotype
IgG1,κ
Immunogen
This PTGS2 antibody is generated from a mouse immunized with a recombiant protein from the human region of human PTGS2.
Reactive Species
M00084-4 is reactive to PTGS2 in Human
Calculated molecular weight
69.0 kDa
Background of PTGS2
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00084-4 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000
Validation Images & Assay Conditions
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Anti-PTGS2 Antibody at 1:2000 dilution + U-87MG whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 69 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Specific Publications For Anti-PTGS2 Antibody (M00084-4)
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