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Product Info Summary
| SKU: | A31772 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-DELE DELE1 Antibody
SKU/Catalog Number
A31772
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-DELE DELE1 Antibody (Catalog # A31772). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Rat.
Storage & Handling
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-DELE DELE1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A31772)
Host
Rabbit
Contents
DELE Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE. The immunogen is located within the first 50 amino acids of DELE.
Reactive Species
A31772 is reactive to KIAA0141 in Human, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
55.9 kDa
Background of KIAA0141
DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A31772 is guaranteed for ELISA, IF, WB Boster Guarantee
Recommend Dilution
DELE antibody can be used for detection of DELE by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of DELE in rat brain tissue lysate with DELE antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
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Immunofluorescence of DELE in human brain tissue with DELE antibody at 20 μg/mL.
Specific Publications For Anti-DELE DELE1 Antibody (A31772)
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