Anti-Angiopoietin-related protein 1 ANGPTL1 Antibody
Rabbit IgG polyclonal antibody for Angiopoietin-related protein 1(ANGPTL1) detection. Tested with WB in Human;Mouse;Rat.
Anti-Angiopoietin-related protein 1 ANGPTL1 Antibody Info At A Glance
|Reactivity:||Human, Mouse, Rat|
|Product Name||Anti-Angiopoietin-related protein 1 ANGPTL1 Antibody
See all Angiopoietin-like Protein 1/ANGPTL1 primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Polyclonal antibody for Angiopoietin like Protein 1/ANGPTL1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. Angiopoietin like Protein 1/ANGPTL1 information: Molecular Weight: 56720 MW; Subcellular Localization: Secreted ; Tissue Specificity: Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach.|
|Cite This Product||Anti-Angiopoietin-related protein 1 ANGPTL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1487)|
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|Anti-Angiopoietin-related protein 1 ANGPTL1 Antibody may replace the following items: sc 135115|sc 365146|sc 271841|sc 161342|sc 161341.|
|Reactivity/Species||Human, Mouse, Rat|
*This antibody is predicted to react with the above species based on antigen sequence similarities. Our Boster Guarantee covers the use of this product with the above species.
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of human ANGPTL1(477-491aa SYSLRAVQMMIKPID), identical to the related rat and mouse sequences.|
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For ANGPTL1 (Source: Uniprot.org, NCBI)
|NCBI Gene Id||9068|
|Species Of This Entry||Human|
|Protein Name||Angiopoietin-related protein 1|
|Alternative Names||Angiopoietin-like Protein 1/ANGPTL1|ANG-3; ANG3angioarrestin; Angiopoietin like Protein 1; angiopoietin Y1; angiopoietin-3; angiopoietin-like 1; Angiopoietin-like Protein 1; angiopoietin-related protein 1; ANGPT3; ANGPTL1; AngY; AngY1; ARP1; ARP1angiopoietin 3; dJ595C2.2 (angiopoietin Y1); dJ595C2.2; KIAA0351; UNQ162|
|Post Tranlational Modifications||Phosphorylation; Oxidation|
|Gene Location||1q25.2, on Chromasome 1, gene sequence: NC_000001.11 (178849535..178871077, complement)|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For ANGPTL1 (Source: Uniprot.org, NCBI)
|Related Diseases||Tumor Angiogenesis; Neoplasms; Pathologic Neovascularization; Malignant Neoplasms; Corneal Diseases; Melanoma; Carcinoma; Cell Transformation, Neoplastic; Multiple Endocrine Neoplasia Type 1; Malignant Paraganglionic Neoplasm; Tumor Progression; Malignant Neoplasm Of Lung; Lung Neoplasms; Corneal Neovascularization; Neoplasm Metastasis; Dyslipidemias; Brain Ischemia; Metastatic Malignant Neoplasm To The Lung; Malignant Neoplasm Of Breast; Glioma|
|Related Pathways||Angiogenesis; Cell Proliferation; Endothelial Cell Proliferation; Secretion; Tube Formation; Protein Secretion; Localization; Cartilage Development; Regeneration; Tissue Development; Fin Regeneration; Cell Cycle; Cell Growth; Wound Healing; Oncogenesis|
|Background||ANGPTL1, Angiopoietin-related protein 1, is a protein that in humans is encoded by the ANGPTL1 gene. Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. ANGPTL1 is widely expressed in human adult tissues as a major 3.0-kb transcript and a less abundant 4.0-kb transcript.|
|Scientific References||PMID: 10025962 by Kim I., et al. Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin-3.|
Our Boster Quality Guarantee for Anti-Angiopoietin-related protein 1 ANGPTL1 Antibody covers its use in the following applications.Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
Lane 1: A549 Cell Lysate
Lane 2: SW620 Cell Lysate
Lane 3: MCF-7 Cell Lysate
Lane 4: MM231 Cell Lysate
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