Anti-Acid-sensing ion channel 3 ASIC3 Antibody

Amiloride-sensitive cation channel 3 antibody

Boster Bio Anti-Acid-sensing ion channel 3 ASIC3 Antibody catalog # PA1938. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 2 publication(s).

Product Info Summary

SKU: PA1938
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, WB

Product Name

Anti-Acid-sensing ion channel 3 ASIC3 Antibody

View all Amiloride-sensitive cation channel 3 Antibodies

SKU/Catalog Number



100 μg/vial




Boster Bio Anti-Acid-sensing ion channel 3 ASIC3 Antibody catalog # PA1938. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Acid-sensing ion channel 3 ASIC3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1938)




Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.




Rabbit IgG


A synthetic peptide corresponding to a sequence at the N-terminus of human ASIC3 (56-73aa FLYQVAERVRYYREFHHQ), different from the related rat and mouse sequences by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.


No cross-reactivity with other proteins

Reactive Species

PA1938 is reactive to ASIC3 in Human, Mouse, Rat


PA1938 is guaranteed for Flow Cytometry, WB Boster Guarantee

Background of Amiloride-sensitive cation channel 3

ASIC3 (Acid-Sensing Ion Channel3), also known as TESTIS SODIUM CHANNEL 1 (TNAC1) or DORSAL ROOT ACID-SENSING ION CHANNEL (DRASIC), is a protein that in humans is encoded by the ASIC3 gene. ASIC3 belongs to a family of acid-sensing channel proteins that are structurally related to epithelial sodium channel proteins and support acid-activated membrane currents. By radiation hybrid analysis, de Weille et al. (1998) mapped the ACCN3 gene to chromosome 7q35. De Weille et al. (1998) found that human ASIC3 supported an H (+)-gated cation current in COS cells with kinetics similar to those of rat Asic3. Babinski et al. (1999) expressed homomeric human ASIC3 channels in Xenopus oocytes and found that rapid reduction in extracellular pH resulted in a biphasic response characterized by a fast and rapidly desensitizing current followed by a slow and sustained current that returned to baseline only on return to physiologic pH.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review


Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Flow Cytometry, 1-3μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For ASIC3 (Source:, NCBI)

Uniprot ID


Gene ID


Gene Name


Full Name

Acid-sensing ion channel 3




amiloride-sensitive sodium channel (TC 1.A.6) family

Alternative Names

Acid-sensing ion channel 3; amiloride-sensitive cation channel 3; amiloride-sensitive cation channel 3, testis; ASIC3hTNaC1; DRASIC; hASIC3; modulatory subunit of ASIC2a; Neuronal amiloride-sensitive cation channel 3; proton-gated cation channel subunit; SLNAC1; Testis sodium channel 1; TNaC1 ASIC3 ACCN3, DRASIC, SLNAC1, TNaC1 acid sensing ion channel subunit 3 acid-sensing ion channel 3|acid sensing (proton gated) ion channel 3|amiloride-sensitive cation channel 3, testis|modulatory subunit of ASIC2a|neuronal amiloride-sensitive cation channel 3|proton-gated cation channel subunit|testis sodium channel 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ASIC3, check out the ASIC3 Infographic

ASIC3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ASIC3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

PA1938 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Effect of knockout of the ASIC3 on cardiovascular reflexes arising from hindlimb muscle in decerebrated rats

Schuhmacher LN, Callejo G, Srivats S, Smith ESJ. J Biol Chem. 2018 Feb 2;293(5):1756-1766. doi: 10.1074/jbc.M117.807859. Epub 2017 Dec 13. Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers

Have you used Anti-Acid-sensing ion channel 3 ASIC3 Antibody?

Submit a review and receive an Amazon gift card.

  • $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
  • $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit A Review

Be the first to review Anti-Acid-sensing ion channel 3 ASIC3 Antibody

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

6 Customer Q&As for Anti-Acid-sensing ion channel 3 ASIC3 Antibody


We are currently using anti-ASIC3 antibody PA1938 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on feline tissues as well?

Verified Customer

Verified customer

Asked: 2019-08-14


The anti-ASIC3 antibody (PA1938) has not been tested for cross reactivity specifically with feline tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-08-14


Is this PA1938 anti-ASIC3 antibody reactive to the isotypes of ASIC3?

Verified Customer

Verified customer

Asked: 2019-05-17


The immunogen of PA1938 anti-ASIC3 antibody is A synthetic peptide corresponding to a sequence at the N-terminus of human ASIC3(56-73aa FLYQVAERVRYYREFHHQ), different from the related rat and mouse sequences by two amino acids. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2019-05-17


We need to test anti-ASIC3 antibody PA1938 on rat right hemisphere of cerebellum for research purposes, then I may be interested in using anti-ASIC3 antibody PA1938 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

T. Krishna

Verified customer

Asked: 2019-04-05


The products we sell, including anti-ASIC3 antibody PA1938, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2019-04-05


Do you have data regarding IF and IHC-P application using PA1938?

Verified customer

Asked: 2019-03-15


We did not get positive staining for the IHC-P test. We do not recommend using the Anti-Acid-Sensing Ion Channel 3 ASIC3 Antibody (PA1938) for IF and IHC-P.

Boster Scientific Support

Answered: 2019-03-18


Would anti-ASIC3 antibody PA1938 work on horse WB with testis?

Verified Customer

Verified customer

Asked: 2018-03-16


Our lab technicians have not tested anti-ASIC3 antibody PA1938 on horse. You can run a BLAST between horse and the immunogen sequence of anti-ASIC3 antibody PA1938 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated horse samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in horse testis in WB, you can get your next antibody for free.

Boster Scientific Support

Answered: 2018-03-16


I am interested in your #PA1938 ASIC3 antibody. May I know if you have data regarding to IF and IHC-P application? Please let me know if you have related information.

Verified Customer

Verified customer

Asked: 2013-12-30


We didn't get positive staining for IHC-P test. This antibody is not recommended to work for

Boster Scientific Support

Answered: 2013-12-30



Total: $315


Ask a question

Get A Quote

Ships directly to USA and Canada. For other regions, visit our distributors page

Bulk Inquiry

Sample Inquiry

In stock
Order Product
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)

$50 fee for conjugation. Antibody size is reduced to 50ug.



Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.