Anti-Acid-sensing ion channel 3 ASIC3 Antibody

Boster Bio Anti-Acid-sensing ion channel 3 ASIC3 Antibody catalog # PA1938. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: PA1938
Size: 100μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, WB

Product Name

Anti-Acid-sensing ion channel 3 ASIC3 Antibody

See all Amiloride-sensitive cation channel 3 products

SKU/Catalog Number

PA1938

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Acid-sensing ion channel 3 ASIC3 Antibody catalog # PA1938. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Acid-sensing ion channel 3 ASIC3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1938)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human ASIC3 (56-73aa FLYQVAERVRYYREFHHQ), different from the related rat and mouse sequences by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PA1938 is reactive to ASIC3 in Human, Mouse, Rat

Applications

PA1938 is guaranteed for Flow Cytometry, WB Boster Guarantee

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive your next antibody/ELISA kit free of charge! Applicable to all scientists world wide.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Flow Cytometry, 1-3μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For ASIC3 (Source: Uniprot.Org, NCBI)

Uniprot ID

Q9UHC3

Gene ID

9311

Gene Name

ASIC3

Full Name

Acid-sensing ion channel 3

Weight

58.905kDa

Superfamily

amiloride-sensitive sodium channel (TC 1.A.6) family

Alternative Names

Acid-sensing ion channel 3; amiloride-sensitive cation channel 3; amiloride-sensitive cation channel 3, testis; ASIC3hTNaC1; DRASIC; hASIC3; modulatory subunit of ASIC2a; Neuronal amiloride-sensitive cation channel 3; proton-gated cation channel subunit; SLNAC1; Testis sodium channel 1; TNaC1 ASIC3 ACCN3, DRASIC, SLNAC1, TNaC1 acid sensing ion channel subunit 3 acid-sensing ion channel 3|acid sensing (proton gated) ion channel 3|amiloride-sensitive cation channel 3, testis|modulatory subunit of ASIC2a|neuronal amiloride-sensitive cation channel 3|proton-gated cation channel subunit|testis sodium channel 1

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on ASIC3, check out the ASIC3 Infographic

ASIC3 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for ASIC3: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

PA1938 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Schuhmacher LN, Callejo G, Srivats S, Smith ESJ. J Biol Chem. 2018 Feb 2;293(5):1756-1766. doi: 10.1074/jbc.M117.807859. Epub 2017 Dec 13. Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers

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6 Customer Q&As for Anti-Acid-sensing ion channel 3 ASIC3 Antibody

Question

We are currently using anti-ASIC3 antibody PA1938 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on feline tissues as well?

Verified Customer

Verified customer

Asked: 2019-08-14

Answer

The anti-ASIC3 antibody (PA1938) has not been tested for cross reactivity specifically with feline tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-08-14

Question

Is this PA1938 anti-ASIC3 antibody reactive to the isotypes of ASIC3?

Verified Customer

Verified customer

Asked: 2019-05-17

Answer

The immunogen of PA1938 anti-ASIC3 antibody is A synthetic peptide corresponding to a sequence at the N-terminus of human ASIC3(56-73aa FLYQVAERVRYYREFHHQ), different from the related rat and mouse sequences by two amino acids. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2019-05-17

Question

We need to test anti-ASIC3 antibody PA1938 on rat right hemisphere of cerebellum for research purposes, then I may be interested in using anti-ASIC3 antibody PA1938 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

T. Krishna

Verified customer

Asked: 2019-04-05

Answer

The products we sell, including anti-ASIC3 antibody PA1938, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2019-04-05

Question

May I know if you have data regarding IF and IHC-P application using PA1938? Please let me know if you have related information.

Verified customer

Asked: 2019-03-15

Answer

We did not get positive staining for the IHC-P test. We do not recommend using the Anti-Acid-Sensing Ion Channel 3 ASIC3 Antibody (PA1938) for IF and IHC-P.

Boster Scientific Support

Answered: 2019-03-18

Question

Would anti-ASIC3 antibody PA1938 work on horse WB with testis?

Verified Customer

Verified customer

Asked: 2018-03-16

Answer

Our lab technicians have not tested anti-ASIC3 antibody PA1938 on horse. You can run a BLAST between horse and the immunogen sequence of anti-ASIC3 antibody PA1938 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated horse samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in horse testis in WB, you can get your next antibody for free.

Boster Scientific Support

Answered: 2018-03-16

Question

I am interested in your #PA1938 ASIC3 antibody. May I know if you have data regarding to IF and IHC-P application? Please let me know if you have related information.

Verified Customer

Verified customer

Asked: 2013-12-30

Answer

We didn't get positive staining for IHC-P test. This antibody is not recommended to work for

Boster Scientific Support

Answered: 2013-12-30

Size

Total: $240

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Ships directly to USA and Canada. For other regions, visit our distributors page

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PA1938
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$240.00

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