Anti-ATF-2 Monoclonal Antibody

ATF2 antibody

Boster Bio Anti-ATF-2 Monoclonal Antibody catalog # M00916-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse. Cited in 1 publication(s).

Product Info Summary

SKU: M00916-1
Size: 100ul
Reactive Species: Human, Mouse
Host: Mouse
Application: ELISA, IHC, WB

Product Name

Anti-ATF-2 Monoclonal Antibody

View all ATF2 Antibodies

SKU/Catalog Number

M00916-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-ATF-2 Monoclonal Antibody catalog # M00916-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ATF-2 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00916-1)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

4F12

Isotype

IgG

Immunogen

Purified recombinant fragment of human ATF-2 expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M00916-1 is reactive to ATF2 in Human, Mouse

Applications

M00916-1 is guaranteed for ELISA, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

54.537kDa

Background of ATF2

TRPC6, also known as TRP6, short transient receptor potential channel 6 and transient receptor potential cation channel subfamily C member 6, is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC6 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C and may not to be activated by intracellular calcium store depletion. Defects in this gene are a cause of focal segmental glomerulosclerosis (FSGS). Expression of this protein has been reported in tissues such as placenta, lung, spleen, ovary, small intestine, and renal podocytes. Immunohistochemistry studies using polyclonal antibodies to this target have shown moderate to strong staining in cell types such as neurons, breast, respiratory, squamous and prostate epithelium, epidermis, placental trophoblasts, dendritic cells, and subsets of immune cells, and faint to moderate staining of adrenal, colon, ganglion cells, hepatocytes, heart, and testis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000

Validation Images & Assay Conditions

Gene/Protein Information For ATF2 (Source: Uniprot.org, NCBI)

Gene Name

ATF2

Full Name

Cyclic AMP-dependent transcription factor ATF-2

Weight

54.537kDa

Superfamily

bZIP family

Alternative Names

activating transcription factor 2formerly; ATF2; cAMP responsive element binding protein 2; cAMP-responsive element-binding protein 2; CREB2; CREBP1; CRE-BP1; cyclic AMP-dependent transcription factor ATF-2; HB16; MGC111558; mXBP; TREB7 ATF2 CRE-BP1, CREB-2, CREB2, HB16, TREB7 activating transcription factor 2 cyclic AMP-dependent transcription factor ATF-2|activating transcription factor 2 splice variant ATF2-var2|cAMP response element-binding protein CRE-BP1|cAMP responsive element binding protein 2, formerly|cAMP-dependent transcription factor ATF-2|cyclic AMP-responsive element-binding protein 2|histone acetyltransferase ATF2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ATF2, check out the ATF2 Infographic

ATF2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ATF2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

M00916-1 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Wu T,Liu Q,Li Y,Li H,Chen L,Yang X,Tang Q,Pu S,Kuang J,Li R,Huang Y,Zhang J,Zhang Z,Zhou J,Huang C,Zhang G,Zhao Y,Zou M,Jiang W,Mo L,He J.Feeding-induced hepatokine, Manf, ameliorates diet-induced obesity by promoting adipose browning via p38 MAPK pathway.J Exp Med.2021 Jun 7;218(6):e20201203.doi:10. 1084/jem. 20201203.PMID:33856409.
Species: Mouse
M00916-1 usage in article: APP:WB, SAMPLE:ADIPOCYTES, DILUTION :1:2000

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Order DetailsPrice
M00916-1-100ul

100ul

$380

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M00916-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$380.00

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