Anti-BIN3 Monoclonal Antibody

BIN3 antibody

Boster Bio Anti-BIN3 Monoclonal Antibody (Catalog # M11817). Tested in ELISA, WB applications. This antibody reacts with Mouse.

Product Info Summary

SKU: M11817
Size: 100ug
Reactive Species: Mouse
Host: Mouse
Application: ELISA, WB

Customers Who Bought This Also Bought

Product Name

Anti-BIN3 Monoclonal Antibody

View all BIN3 Antibodies

SKU/Catalog Number

M11817

Size

100ug

Form

Liquid (sterile filtered)

Description

Boster Bio Anti-BIN3 Monoclonal Antibody (Catalog # M11817). Tested in ELISA, WB applications. This antibody reacts with Mouse.

Storage & Handling

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening. (Ship on dry ice.)

Cite This Product

Anti-BIN3 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M11817)

Host

Mouse

Contents

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide

Clonality

Monoclonal

Clone Number

Clone: 3A4

Isotype

IgG1

Immunogen

Anti-BIN3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with a full length human BIN3 recombinant protein followed by hybridoma development.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M11817 is reactive to BIN3 in Mouse

Reconstitution

Calculated molecular weight

29665 MW

Background of BIN3

BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non–Hodgkin’s lymphomas and various epithelial tumors. Study in mouse suggests that homozygous inactivation of Bin3 causes cataracts and an increased susceptibility to lymphomas during aging.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

M11817 is guaranteed for ELISA, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ELISA: 1:5000 - 1:50000
IP: 10-100 µL
WB: 1:500-1:1500

Validation Images & Assay Conditions

Gene/Protein Information For BIN3 (Source: Uniprot.org, NCBI)

Gene Name

BIN3

Full Name

Bridging integrator 3

Weight

29665 MW

Alternative Names

BIN3, Bridging integrator 3, BIN-3, BIN 3, BIN3, anti-BIN-3 BIN3 bridging integrator 3 bridging integrator 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on BIN3, check out the BIN3 Infographic

BIN3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for BIN3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

No publications found for M11817

*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.

Have you used Anti-BIN3 Monoclonal Antibody?

Submit a review and receive an Amazon gift card.

  • $30 for a review with an image

0 Reviews For Anti-BIN3 Monoclonal Antibody

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

6 Customer Q&As for Anti-BIN3 Monoclonal Antibody

Question

Would anti-BIN3 Monoclonal antibody M11817 work on pig WB with lung skin?

Verified Customer

Verified customer

Asked: 2020-01-24

Answer

Our lab technicians have not validated anti-BIN3 Monoclonal antibody M11817 on pig. You can run a BLAST between pig and the immunogen sequence of anti-BIN3 Monoclonal antibody M11817 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated pig samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in pig lung skin in WB, you can get your next antibody for free.

Boster Scientific Support

Answered: 2020-01-24

Question

Is this M11817 anti-BIN3 Monoclonal antibody reactive to the isotypes of BIN3?

Verified Customer

Verified customer

Asked: 2019-11-22

Answer

The immunogen of M11817 anti-BIN3 Monoclonal antibody is anti-BIN3 (MOUSE) Monoclonal antibody was produced in mouse by repeated immunizations with a full legnth human BIN3 recombinant protein followed by hybridoma development. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2019-11-22

Question

Will anti-BIN3 Monoclonal antibody M11817 work for IP with cervix carcinoma?

Verified Customer

Verified customer

Asked: 2018-04-04

Answer

According to the expression profile of cervix carcinoma, BIN3 is highly expressed in cervix carcinoma. So, it is likely that anti-BIN3 Monoclonal antibody M11817 will work for IP with cervix carcinoma.

Boster Scientific Support

Answered: 2018-04-04

Question

We are currently using anti-BIN3 Monoclonal antibody M11817 for human tissue, and we are content with the IP results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on primate tissues as well?

M. Roberts

Verified customer

Asked: 2018-01-16

Answer

The anti-BIN3 Monoclonal antibody (M11817) has not been validated for cross reactivity specifically with primate tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in primate you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2018-01-16

Question

See attached the WB image, lot number and protocol we used for cervix carcinoma using anti-BIN3 Monoclonal antibody M11817. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2017-11-17

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2017-11-17

Question

I see that the anti-BIN3 Monoclonal antibody M11817 works with IP, what is the protocol used to produce the result images on the product page?

F. Zhao

Verified customer

Asked: 2016-10-25

Answer

You can find protocols for IP on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2016-10-25

Order DetailsPrice
M11817-100uL

100uL

$646

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
In stock
Order Product
M11817
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$646.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.