Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody
Rabbit IgG polyclonal antibody for C-C motif chemokine 4(CCL4) detection. Tested with WB in Mouse.
Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody Info At A Glance
|Product Name||Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody
See all CCL4/MIP-1 beta primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Polyclonal antibody for MIP 1BETA/CCL4 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Mouse. MIP 1BETA/CCL4 information: Molecular Weight: 10168 MW; Subcellular Localization: Secreted.|
|Cite This Product||Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1379)|
|Similar Products From
|Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody may replace the following items: sc 130330|sc 1385|sc 367243.|
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For Ccl4 (Source: Uniprot.org, NCBI)
|NCBI Gene Id||20303|
|Species Of This Entry||Mouse|
|Protein Name||C-C motif chemokine 4|
|Superfamily||intercrine beta (chemokine CC) family|
|Alternative Names||CCL4/MIP-1 beta|ACT2; ACT-2; AT744.1; C-C motif chemokine 4; CCL4; chemokine (C-C motif) ligand 4; Exodus-3; G-26 T-lymphocyte-secreted protein; G-26; HC21; LAG1; LAG-1; Lymphocyte activation gene 1 protein; Macrophage inflammatory protein 1-beta; MIP1 beta; MIP-1 beta; MIP1B; MIP1B1; MIP-1-beta; MIP-1-beta(1-69); PAT 744; Protein H400; SCYA2; SCYA4; secreted protein G-26; SIS-gamma; small inducible cytokine A4 (homologous to mouse Mip-1b); Small-inducible cytokine A4; T-cell activation protein 2|
|Post Tranlational Modifications||Phosphorylation; Cleavage; Oxidation; Acetylation; Demethylation; Carboxylation; Reduction; Phosphorothioation; Citrullination; Methylation|
|Gene Location||11 C|11 51.09 cM, on Chromasome 11, gene sequence:|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For Ccl4 (Source: Uniprot.org, NCBI)
|Protein Function||Monokine with inflammatory and chemokinetic properties.|
|Related Diseases||Inflammation; Cholangiocarcinoma; Hiv Infections; Toxic Effect Of Carbon Tetrachloride; Malignant Neoplasms; Neoplasms; Infective Disorder; Autoimmune Reaction; Drug-induced Liver Injury; Inflammatory Response; Tissue Adhesions; Immunologic Deficiency Syndromes; Fibrosis; Virus Diseases; Injury To Liver; Liver Cirrhosis; Arthritis; Liver Damage; Liver Diseases|
|Related Pathways||Secretion; Immune Response; Pathogenesis; Chemotaxis; Chemokine Production; Inflammatory Response; Cell Migration; Regeneration; Cell Proliferation; Cytokine Production; Cell Activation; Innate Immune Response; Chemokine Secretion; Cytokine Secretion; Phagocytosis; Angiogenesis; Leukocyte Migration; Cell Death; Viral Replication; Sensitization|
|Background||Chemokine(C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize MIP-1-beta. Modi et al.(1991) assigned the SCYA4 gene to a slightly more distal location than had Irving et al.(1990): 17q21-q23 rather than 17q11-q21.|
|Scientific References||PMID: 3058856 by Sherry B., et al. Resolution of the two components of macrophage inflammatory protein 1, and cloning and characterization of one of those components, macrophage inflammatory protein 1 beta.|
PMID: 2521353 by Brown K.D., et al. A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast- derived inflammatory agents, growth factors, and indicators of various activation processes.
Our Boster Quality Guarantee for Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody covers its use in the following applications.Western blot, 0.1-0.5μg/ml, Mouse
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
Lane 1: Mouse Spleen Tissue Lysate
Lane 2: Mouse Cardiac Muscle Tissue Lysate
Lane 3: Mouse Lung Tissue Lysate
Lane 4: Mouse Kidney Tissue Lysate
Lane 5: Mouse Skeletal Muscle Tissue Lysate
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
- Western Blottting Resource Center
- Immunohistochemistry Resource Center
- Flow Cytometry Technical Resource Center
Other Recommended Resources
Here are featured tools and databases that you might find useful.
Order Product (PA1379)
Domestically in USA and Canada, ships next business day if available in stock.
Note: sample size takes longer to process, average 5-7 days.
All Boster antibodies and ELISA kits are guaranteed to meet the specifications on the data sheet.See Details
Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.Download Free PDFs Now
Guaranteed product quality
We promise all of our products perform as described in datasheets.