Anti-CD123 (S47) IL3RA Antibody

IL-3R alpha/CD123 antibody

Boster Bio Anti-CD123 (S47) IL3RA Antibody catalog # A04307S47. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A04307S47
Size: 100ul
Reactive Species: Human
Host: Rabbit
Application: WB

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Product Name

Anti-CD123 (S47) IL3RA Antibody

View all IL-3R alpha/CD123 Antibodies

SKU/Catalog Number

A04307S47

Size

100ul

Form

Liquid

Description

Boster Bio Anti-CD123 (S47) IL3RA Antibody catalog # A04307S47. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CD123 (S47) IL3RA Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04307S47)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human PERQ2 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04307S47 is reactive to IL3RA in Human

Applications

A04307S47 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

43.33kDa

Background of IL-3R alpha/CD123

Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes.

Ortega A., J. Biol. Chem. 278:3040-3047(2003).
Nagase T., DNA Res. 2:37-43(1995).
Mungall A.J., Nature 425:805-811(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000

Validation Images & Assay Conditions

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Gene/Protein Information For IL3RA (Source: Uniprot.org, NCBI)

Gene Name

IL3RA

Full Name

Interleukin-3 receptor subunit alpha

Weight

43.33kDa

Superfamily

type I cytokine receptor family

Alternative Names

CD123 antigen; CD123; hIL3Ra; hIL-3Ra; IL-3 R alpha; IL-3 receptor subunit alpha; IL3R alpha; IL-3R alpha; IL-3R subunit alpha; IL3R; IL3RA; IL-3Ra; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; MGC34174 IL3RA CD123, IL3RY, IL3RX, IL3RY, hIL-3Ra, IL3RA interleukin 3 receptor subunit alpha interleukin-3 receptor subunit alpha|CD123 antigen|IL-3 receptor subunit alpha|IL-3R subunit alpha|IL-3R-alpha|IL-3RA|interleukin 3 receptor, alpha (low affinity)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on IL3RA, check out the IL3RA Infographic

IL3RA infographic

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In this infographic, you will see the following information for IL3RA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A04307S47-100ul

100ul

$405

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