Product Info Summary
SKU: | A04307S47 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-CD123 (S47) IL3RA Antibody
View all IL-3R alpha/CD123 Antibodies
SKU/Catalog Number
A04307S47
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CD123 (S47) IL3RA Antibody catalog # A04307S47. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CD123 (S47) IL3RA Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04307S47)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human PERQ2 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04307S47 is reactive to IL3RA in Human
Applications
A04307S47 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
43.33kDa
Background of IL-3R alpha/CD123
Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes.
Ortega A., J. Biol. Chem. 278:3040-3047(2003).
Nagase T., DNA Res. 2:37-43(1995).
Mungall A.J., Nature 425:805-811(2003).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For IL3RA (Source: Uniprot.org, NCBI)
Gene Name
IL3RA
Full Name
Interleukin-3 receptor subunit alpha
Weight
43.33kDa
Superfamily
type I cytokine receptor family
Alternative Names
CD123 antigen; CD123; hIL3Ra; hIL-3Ra; IL-3 R alpha; IL-3 receptor subunit alpha; IL3R alpha; IL-3R alpha; IL-3R subunit alpha; IL3R; IL3RA; IL-3Ra; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; MGC34174 IL3RA CD123, IL3RY, IL3RX, IL3RY, hIL-3Ra, IL3RA interleukin 3 receptor subunit alpha interleukin-3 receptor subunit alpha|CD123 antigen|IL-3 receptor subunit alpha|IL-3R subunit alpha|IL-3R-alpha|IL-3RA|interleukin 3 receptor, alpha (low affinity)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL3RA, check out the IL3RA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL3RA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CD123 (S47) IL3RA Antibody (A04307S47)
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No publications found for A04307S47
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