Anti-Connexin 43 (phospho-S367) GJA1 Antibody

Connexin 43/GJA1 antibody

Boster Bio Anti-Connexin 43 (phospho-S367) GJA1 Antibody catalog # A00599S367. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A00599S367
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-Connexin 43 (phospho-S367) GJA1 Antibody

View all Connexin 43/GJA1 Antibodies

SKU/Catalog Number

A00599S367

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Connexin 43 (phospho-S367) GJA1 Antibody catalog # A00599S367. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Connexin 43 (phospho-S367) GJA1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00599S367)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Connexin 43 around the phosphorylation site of S265.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A00599S367 is reactive to GJA1 in Human, Mouse, Rat

Applications

A00599S367 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

43.008kDa

Background of Connexin 43/GJA1

Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment; the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes By similarity. Binds to chromatin and interacts selectively with histone H3 that is not methylated at 'Lys-4', not phosphorylated at 'Thr-3' and not methylated at 'Arg-2'. Functions as a sensor of histone H3 modifications that are important for the epigenetic regulation of gene expression. Functions as a transcriptional activator and promotes the expression of otherwise tissue-specific self-antigens in the thymus, which is important for self tolerance and the avoidance of autoimmune reactions.

Nagamine K., Nat. Genet. 17:393-398(1997).
Aaltonen J., Nat. Genet. 17:399-403(1997).
Hattori M., Nature 405:311-319(2000).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200

Validation Images & Assay Conditions

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Gene/Protein Information For GJA1 (Source: Uniprot.org, NCBI)

Gene Name

GJA1

Full Name

Gap junction alpha-1 protein

Weight

43.008kDa

Superfamily

connexin family

Alternative Names

Connexin 43; connexin-43; CX43; CX43gap junction protein, alpha-like; DFNB38; Gap junction 43 kDa heart protein; gap junction alpha-1 protein; gap junction protein, alpha 1, 43kDa (connexin 43); gap junction protein, alpha 1, 43kDa; GJA1; GJAL; HSS; ODD; ODDD; ODOD; SDTY3 GJA1 AVSD3, CMDR, CX43, EKVP, EKVP3, GJAL, HLHS1, HSS, ODDD, PPKCA gap junction protein alpha 1 gap junction alpha-1 protein|connexin-43|gap junction 43 kDa heart protein|gap junction protein, alpha 1, 43kDa

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on GJA1, check out the GJA1 Infographic

GJA1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GJA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00599S367-100ul

100ul

$482

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