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- Table of Contents
GJA1 Antibodies
AND GJA1 ELISA kits, GJA1 Proteins
Many biological assays use antibodies to detect GJA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GJA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GJA1 antibodies...
Designing a Western blot for GJA1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GJA1 Western Blot GuideGJA1 Infographic by Boster Bio
All GJA1 Products
Product
Figures
Specificity
Applications
Price
Anti-Connexin 43/GJA1 Antibody Picoband®
22 Citations
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A00599
100 μg/vial
Cat # A00599
100 μg/vial
Anti-Connexin 43/GJA1 Antibody Picoband®
13 Citations
Human, Mouse, Rat
IF, IHC, WB
$370
Cat # PA1026
100 μg/vial
Cat # PA1026
100 μg/vial
Anti-PPAR alpha/PPARA Antibody Picoband®
12 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00600-2
100 μg/vial
Cat # A00600-2
100 μg/vial
Human, Monkey
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00603-2
100 μg/vial
Cat # A00603-2
100 μg/vial
Anti-Prolactin/PRL Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, WB
$370
Cat # A00601-1
100 µg/vial
Cat # A00601-1
100 µg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00599-1
20μL, 40μL, 100μL, 200μL
Cat # M00599-1
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA
$540
Cat # EKC2378
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2378
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1134
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1134
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00599S368
100ul
Cat # A00599S368
100ul
Human, Mouse, Rat
ELISA, IF, IHC
$380
Cat # A00599S261
100ul
Cat # A00599S261
100ul
GJA1 Overview
Facts about Gap junction alpha-1 protein.
Gap junction alpha-1 protein (GJA1)
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and making them contract (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | GJA1 |
| Uniprot: | P17302 |
| Entrez: | 2697 |
Family
| Belongs to: |
|---|
| connexin family |
Alternative Names
Connexin 43; connexin-43; CX43; CX43gap junction protein, alpha-like; DFNB38; Gap junction 43 kDa heart protein; gap junction alpha-1 protein; gap junction protein, alpha 1, 43kDa (connexin 43); gap junction protein, alpha 1, 43kDa; GJA1; GJAL; HSS; ODD; ODDD; ODOD; SDTY3
Molecular Weight
Mass (kDA):
43.008 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q22.31 |
| Sequence: | 6; NC_000006.12 (121435646..121449727) |
Tissue Specificity
Expressed in the heart and fetal cochlea.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum. Localizes at the intercalated disk (ICD) in cardiomyocytes and the proper localization at ICD is dependent on TMEM65.
Diseases
- Dysplasia
- Oculo-dento-digital Syndrome
- Eye Abnormalities
- Syndactyly
- Malignant Neoplasms
- Tooth Abnormalities
- Cardiac Arrhythmia
- Neoplasms
- Craniofacial Abnormalities
- Tissue Adhesions
- Limb Deformities, Congenital
- Dental Enamel Hypoplasia
- Heart Failure
Interacting Proteins
- TJP1
Pathways
- Localization
- Cell Proliferation
- Spermatogenesis
- Cell Adhesion
- Parturition
- Ovulation
- Cell Differentiation
- Fertilization
- Cell Migration
- Transport
- Cell Development
- Methylation
- Secretion
PTMs
- Phosphorylation
- Methylation
- Acetylation
- Demethylation
- Nitrosylation
Research Areas
- Cancer
- Core ESC-Like Genes
- Neuronal Cell Markers
- Neuroscience
- Phospho-Specific
- Signal Transduction
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GJA1
bosterbio.com/bosterbio-gene-info-cards/GJA1
References
PMID: 1696265 by Fishman G.I., et al. Molecular characterization and functional expression of the human cardiac gap junction channel.
PMID: 1646158 by Fishman G.I., et al. The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures.
25 Publications of Boster GJA1 Antibodies & ELISA Kits
- PubMed ID: 10.7150/thno.60160, Iron Oxide Nanoparticles Promote Cx43-Overexpression of Mesenchymal Stem Cells f...
- PubMed ID: 10.3892/mmr.2012.1185, Recombinant human brain natriuretic peptide therapy combined with bone mesenchym...
- PubMed ID: 10.3233/BME-141214, Expression of Cx43 and Pax3 proteins in the human placental villi and decidua du...
- PubMed ID: 10.1186/1423-0127-19-6, Engineered myocardial tissues constructed in vivo using cardiomyocyte-like cells...
- PubMed ID: 10.1159/000095501, Fibrosis of Collagen I and Remodeling of Connexin 43 in Atrial Myocardium of Pat...
- PubMed ID: 10.1016/j.theriogenology.2021.09.008, LIF and bFGF enhanced chicken primordial follicle activation by Wnt/β-catenin p...
- PubMed ID: 10.1016/j.reprotox.2012.12.002, Apocynin and raisanberine alleviate intermittent hypoxia induced abnormal StAR a...
- PubMed ID: 10.1016/j.mce.2017.01.020, Mitochondrial Uncoupling Protein 2 in human cumulus cells is associated with reg...
- PubMed ID: 10.1016/j.ejphar.2013.09.028, AQP4 KO exacerbating renal dysfunction is mediated by endoplasmic reticulum stre...
- PubMed ID: 10.1016/j.bbrc.2016.10.115, Ectoderm mesenchymal stem cells promote differentiation and maturation of oligod...
- PubMed ID: 10.1016/j.bbrc.2009.01.173, Chemical and physical stimuli induce cardiomyocyte differentiation from stem cel...
- PubMed ID: 10.1016/j.acthis.2009.02.001, Differential expression of connexin 43 in human autoimmune thyroid disease
- PubMed ID: , Perineurium-like sheath derived from long-term surviving mesenchymal stem cells ...
- PubMed ID: 32343674, Liu Y,Bai H,Guo F,Thai PN,Luo X,Zhang P,Yang C,Feng X,Zhu D,Guo J,Liang P,Xu Z,Y...
- PubMed ID: 31773683, Effect of celecoxib on protein expression of FAK and Cx43 in DMBA induced rat to...
- PubMed ID: 27983986, Ectoderm mesenchymal stem cells promote differentiation and maturation of oligod...
- PubMed ID: 27575818, Effect of Novel Gasotransmitter hydrogen sulfide on renal fibrosis and connexins...
- PubMed ID: 26450928, miR-381suppresses C/EBP?-dependent Cx43 expression in breast cancer cells
- PubMed ID: 26283635, Identification of miR-200a as a novel suppressor of connexin 43in breast cancer ...
- PubMed ID: 26775665, Argirein alleviates stress-induced and diabetic hypogonadism in rats via normali...
- PubMed ID: 22426698, CPU86017-RS attenuate hypoxia-induced testicular dysfunction in mice by normaliz...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page