Anti-COX1/Cyclooxygenase 1/PTGS1 Antibody Picoband™

COX-1 antibody

Boster Bio Anti-COX1/Cyclooxygenase 1/PTGS1 Antibody Picoband™ catalog # PB9002. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 7 publication(s).

Product Info Summary

SKU: PB9002
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IHC, WB

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Product Name

Anti-COX1/Cyclooxygenase 1/PTGS1 Antibody Picoband™

View all COX-1 Antibodies

SKU/Catalog Number

PB9002

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-COX1/Cyclooxygenase 1/PTGS1 Antibody Picoband™ catalog # PB9002. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-COX1/Cyclooxygenase 1/PTGS1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9002)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human COX1 recombinant protein (Position: E318-L599). Human COX1 shares 90% and 89% amino acid (aa) sequences identity with mouse and rat COX1, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9002 is reactive to PTGS1 in Human, Mouse, Rat

Applications

PB9002 is guaranteed for Flow Cytometry, IHC, WB Boster Guarantee

Observed Molecular Weight

65-72 kDa

Calculated molecular weight

68.686kDa

Background of COX-1

Cyclooxygenase 1 (COX1), also known as Prostaglandin-endoperoxide synthase (PTGS1) or mitochondrial cytochrome c oxidase subunit 1, is the key enzyme in prostaglandin biosynthesis. The gene was approximately 40 kb long, with 11 protein-coding exons. There were 599 amino acid residues with a calculated molecular mass of approximately 68 kD. By analysis of a human/hamster somatic hybrid DNA panel, it was demonstrated that the PTGS1 gene maps to chromosome 9. Human prostaglandin endoperoxide synthase exhibited 91% amino acid identity with the sheep enzyme. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, Mouse, Rat, By Heat
Flow Cytometry, 1-3 μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For PTGS1 (Source: Uniprot.org, NCBI)

Gene Name

PTGS1

Full Name

Prostaglandin G/H synthase 1

Weight

68.686kDa

Superfamily

prostaglandin G/H synthase family

Alternative Names

COX1; COX-1; COX1PGG/HS; COX3; cyclooxygenase-1; EC 1.14.99.1; PCOX1; PGH synthase 1; PGHS1; PGHS-1PHS1; PHS 1; prostaglandin G/H synthase 1; prostaglandin G/H synthase and cyclooxygenase; Prostaglandin H2 synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase andcyclooxygenase); Prostaglandin-endoperoxide synthase 1; PTGHS; PTGS1 PTGS1 COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS prostaglandin-endoperoxide synthase 1 prostaglandin G/H synthase 1|PGH synthase 1|cyclooxygenase-1|prostaglandin H2 synthase 1|prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PTGS1, check out the PTGS1 Infographic

PTGS1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PTGS1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9002 has been cited in 7 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Preparation and Characterization of a Novel Aspirin Derivative with Anti-Thrombotic and Gastric Mucosal Protection Properties

Down-Regulation of Cyclooxygenase-2 is Involved in Ischemic Postconditioning Protection Against Renal Ischemia Reperfusion Injury in Rats

Dietary supplementation with Celecoxib to prevent the welfare problem of tibial dyschondroplasia in broiler chickens

Aspirin Inhibits Fractalkine Expression in Atherosclerotic Plaques and Reduces Atherosclerosis in ApoE Gene Knockout Mice

Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone

Tolerance of neurite outgrowth to Rho kinase inhibitors decreased by cyclooxygenase-2 inhibitor

Preparation and Characterization of a Novel Aspirin Derivative with Anti-Thrombotic and Gastric Mucosal Protection Properties

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7 Customer Q&As for Anti-COX1/Cyclooxygenase 1/PTGS1 Antibody Picoband™

Question

Can PB9002 be used for mouse samples?

Verified customer

Asked: 2020-11-30

Answer

Our lab worked on mouse samples with the Anti-COX1/Cyclooxygenase 1/PTGS1 Antibody Picoband™ (PB9002) and failed to observe specific target band.

Boster Scientific Support

Answered: 2020-11-30

Question

See attached the WB image, lot number and protocol we used for hippocampus trachea using anti-COX1/Cyclooxygenase 1/PTGS1 antibody PB9002. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2019-11-18

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-11-18

Question

We are currently using anti-COX1/Cyclooxygenase 1/PTGS1 antibody PB9002 for human tissue, and we are well pleased with the IHC results. The species of reactivity given in the datasheet says human, rat. Is it likely that the antibody can work on zebrafish tissues as well?

Verified Customer

Verified customer

Asked: 2019-08-20

Answer

The anti-COX1/Cyclooxygenase 1/PTGS1 antibody (PB9002) has not been tested for cross reactivity specifically with zebrafish tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-08-20

Question

Do you have a BSA free version of anti-COX1/Cyclooxygenase 1/PTGS1 antibody PB9002 available?

L. Jha

Verified customer

Asked: 2019-05-09

Answer

We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-COX1/Cyclooxygenase 1/PTGS1 antibody PB9002 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.

Boster Scientific Support

Answered: 2019-05-09

Question

you antibody to test anti-COX1/Cyclooxygenase 1/PTGS1 antibody PB9002 on human hippocampus trachea for research purposes, then I may be interested in using anti-COX1/Cyclooxygenase 1/PTGS1 antibody PB9002 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

J. Jones

Verified customer

Asked: 2016-12-23

Answer

The products we sell, including anti-COX1/Cyclooxygenase 1/PTGS1 antibody PB9002, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2016-12-23

Question

Thanks for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for hippocampus trachea using anti-COX1/Cyclooxygenase 1/PTGS1 antibody PB9002. Let me know if you need anything else.

W. Carter

Verified customer

Asked: 2016-01-14

Answer

We appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2016-01-14

Question

Is a blocking peptide available for product anti-COX1/Cyclooxygenase 1/PTGS1 antibody (PB9002)?

P. Edwards

Verified customer

Asked: 2013-07-04

Answer

We do provide the blocking peptide for product anti-COX1/Cyclooxygenase 1/PTGS1 antibody (PB9002). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2013-07-04

Order DetailsPrice
PB9002

100μg

$370
PB9002-10ug

10μg sample (liquid)

$99
PB9002-Biotin

100 μg Biotin conjugated

$570
PB9002-Cy3

100 μg Cy3 conjugated

$570
PB9002-Dylight488

100 μg Dylight488 conjugated

$570
PB9002-Dylight550

100 μg Dylight550 conjugated

$570
PB9002-Dylight594

100 μg Dylight594 conjugated

$570
PB9002-FITC

100 μg FITC conjugated

$570
PB9002-HRP

100 μg HRP conjugated

$570
PB9002-APC

100 μg APC conjugated

$670
PB9002-PE

100 μg PE conjugated

$670
PB9002-carrier-free

Carrier Free

$370

More conjugates/formats

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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