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Product Info Summary
| SKU: | M01102-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Primate |
| Host: | Mouse |
| Application: | Flow Cytometry, IHC-F |
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Product info
Product Name
Anti-Hu CD41a Purified ITGA2B Monoclonal Antibody
SKU/Catalog Number
M01102-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD41a Purified ITGA2B Monoclonal Antibody (Catalog# M01102-1). Tested in Flow Cytometry, IHC-F application(s). This antibody reacts with Primate, Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD41a Purified ITGA2B Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01102-1)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
HIP8
Isotype
Mouse IgG1
Immunogen
The antibody HIP8 reacts with an extracellular epitope on alpha (a) subunit of CD41 (heavy chain; 120 kDa). CD41 is mainly expressed on platelets and megakaryocytes. The antibody HIP8 blocks platelet aggregation and completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. HIP8 is useful in the morphological and physiological studies o platelets and megakaryocytes.
Reactive Species
M01102-1 is reactive to ITGA2B in Human, Primate
Observed Molecular Weight
42 kDa
Calculated molecular weight
113.4 kDa
Background of ITGA2B
CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M01102-1 is guaranteed for Flow Cytometry, IHC-F Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 µg/ml
Validation Images & Assay Conditions
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Flow cytometry (surface staining) of human peripheral blood cells with anti-CD41a (HIP8) purified, GAM-APC.
Specific Publications For Anti-Hu CD41a Purified ITGA2B Monoclonal Antibody (M01102-1)
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