Anti-Matrilin-3 MATN3 Antibody

Product Name

Anti-Matrilin-3 MATN3 Antibody

View all MATN3 Antibodies

SKU/Catalog Number

A04271

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Matrilin-3 MATN3 Antibody (Catalog # A04271). Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

MATN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Matrilin-3 MATN3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04271)

Host

Rabbit

Contents

MATN3 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

MATN3 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human MATN3. The immunogen is located within amino acids 400 - 450 of MATN3.

Reactive Species

A04271 is reactive to MATN3 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

52.8 kDa

Background of MATN3

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A04271 is guaranteed for ELISA, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

MATN3 antibody can be used for detection of Matn3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information MATN3

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