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- Table of Contents
GRIN1 antibody (PA1222) performs well in IHC, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 8 Publications
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Anti-NMDAR1 antibody, PA1222, IHC(P)
IHC(P): Rat Brain Tissue
IHC(P): Rat Brain Tissue
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Anti-NMDAR1/GRIN1 Antibody Picoband®
GRIN1 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | IHC, WB |
Tested Applications
GRIN1 antibody was positively detected by WB in:
Rat Brain Tissue, Rat Brain Tissue, Rat Liver Tissue, Rat Heart Tissue, MM453 Cell, MM231 Cell, HELA Cell
Suggested blocking solution with 5% non-fat milk or BSA; (*)Recommended protein loading: 20-40 ug per lane
GRIN1 antibody was positively detected by IHC in:
Rat Brain Tissue
Use TE buffer pH 9.0 for antigen retrieval; (*) citrate buffer pH 6.0 is an alternative.
Recommend Dilution
Application
Dilution
Species
Immunohistochemistry (Paraffin-embedded Section)
0.5-1μg/ml
Human, Rat, Mouse
Western blot
0.1-0.5μg/ml
Human, Rat, Mouse
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Reactive Data
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WB
IHC
IF
Rat
Tested
Tested
Recommend
Human
Predicted
Predicted
Predicted
Mouse
Predicted
Predicted
Predicted
Bovine
Predicted
Predicted
Predicted
Sheep
Predicted
Predicted
Predicted
Dog
Predicted
Predicted
Predicted
Monkey
Predicted
Predicted
Predicted
Product Information
Product Name
Anti-NMDAR1/GRIN1 Antibody Picoband®
View all GRIN1 Antibodies
View all GRIN1 Antibodies
Form
Lyophilized
Uniprot
Gene ID
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Host
Rabbit
Contents
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human NMDAR1, identical to the related rat and mouse sequences.
Cross-Reactivity
No cross-reactivity with other proteins
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
110 kDa
Calculated Molecular Weight
105.4 kDa
Background of GRIN1
Glutamate [NMDA] receptor subunit zeta-1 is a protein that in humans is encoded by the GRIN1 gene. The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
Cite This Product
Anti-NMDAR1/GRIN1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1222)
Antibody Homology Across Species
The results generated by this homology analysis tool for commonly used animal species are shown below. For unlisted species, please refer to the homology analysis between the immunogen sequence and the corresponding species.
A homology of ≥90% is recommended. Generally, higher homology indicates a greater potential for cross-species reactivity. However, protein expression levels may vary among different species, tissues, and cell types. Therefore, the homology analysis results are for reference only and do not guarantee antibody cross-reactivity or experimental performance.
Human
100%
High Homology
Mouse
100%
High Homology
Rat
100%
High Homology
Cow
100%
High Homology
Sheep
100%
High Homology
Dog
100%
High Homology
Monkey
100%
High Homology
Zebrafish
44%
Low homology
Drosophila
17%
Low homology
Homology ≥ 90%High Homology
70% ≤ Homology < 90%Moderate Homology
Homology < 70%Low homology
Protocols
Western Blot protocol for GRIN1 antibody
Immunohistochemistry (IHC) protocol for GRIN1 antibody
Publications
Application:
Species:
Elevated Release of Presynaptic Glutamate: The Potential Pathogenesis of Anti-NMDAR Encephalitis-Associated Seizures
Published: 2025-10-17
Journal: CNS Neuroscience & Therapeutics
Application: ICC,IHC,WB
Impact Factor: 5.00
Species: Mouse,Rat
PMID: 41104530
Ovarian teratomas causing anti-N-methyl-D-aspartate receptor encephalitis: a case series from west China
Published: 2025-05-13
Journal: Translational Cancer Research
Application: IHC
Impact Factor: 1.70
Species: Human
PMID: 40530142
The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysfunction
Published: 2018-04-05
Journal: BMC Anesthesiology
Application: IHC,WB
Impact Factor: 1.79
Species: Rat
PMID: 29621970
The excitotoxity of NMDA receptor NR2D subtype mediates human fetal lung fibroblasts proliferation and collagen production
Published: 2017-10-05
Journal: TOXICOLOGY IN VITRO
Application: IF
Impact Factor: 2.87
Species: Human
PMID: 28987794
Effect of hippocampal L‑NBP on BDNF and TrkB expression and neurological function of vascular dementia rats
Published: 2017-09-20
Journal: Molecular Medicine Reports
Application: IHC
Impact Factor: 1.69
Species: Rat
PMID: 28944854
Mechanisms responsible for the effect of median nerve electrical stimulation on traumatic brain injury-induced coma: orexin-A-mediated N-methyl-D-aspartate receptor subunit NR1 upregulation
Published: 2016-06-01
Journal: Neural Regeneration Research
Application: WB,IHC
Impact Factor: 0.97
Species: Rat
PMID: 27482224
Individual and combined effects of rhynchophylline and ketamine on proliferation, NMDAR1 and GluA2/3 protein expression in PC12 cells
Published: 2013-01-23
Journal: FITOTERAPIA
Application: IF
Impact Factor: 2.23
Species: Rat
PMID: 23352746
Expression of N-methyl-d-aspartate receptor 1 and its phosphorylated state in basal ganglia of a neonatal piglet hypoxic-ischemic brain injury model: A controlled study of 1H MRS
Published: 2012-01-18
Journal: EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
Application: IHC
Impact Factor: 2.12
Species: Pig
PMID: 22261079
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PA1222
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00
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We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Sep 25, 2026