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Product Info Summary
|Reactive Species:||Human, Mouse, Rat|
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Boster Bio Anti-NMDAR2B/GRIN2B Antibody catalog # PA1059. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-NMDAR2B/GRIN2B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1059)
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
A synthetic peptide corresponding to a sequence at the C-terminus of human NMDAR2B (1131-1146aa, DFYLDQFRTKENSPHW), identical to the related mouse and rat sequence.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross reactivity with other proteins
PA1059 is reactive to GRIN2B in Human, Mouse, Rat
PA1059 is guaranteed for WB Boster Guarantee
Background of GRIN2B
The N-methyl-D-aspartate receptor 2B, also names as GRIN2B. The sequence of the predicted 1,484-amino acid human protein is 98% and 96% identical to the sequences of the rat and mouse Nmdar2b proteins, respectively. Nmdar2B gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically. Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12 overexpression of NMDA receptor 2B (NR2B) in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100 Hz.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human
Validation Images & Assay Conditions
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Anti-NMDAR2B antibody, PA1059, Western blotting
Lane 1: Rat Brain Tissue Lysate
Lane 2: Rat Brain Tissue Lysate
Lane 3: Mouse Brain Tissue Lysate
Lane 4: Mouse Brain Tissue Lysate
Gene/Protein Information For GRIN2B (Source: Uniprot.Org, NCBI)
Glutamate receptor ionotropic, NMDA 2B
glutamate-gated ion channel (TC 1.A.10.1) family
glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; hNR3; MGC142180; NMDAR2BMGC142178; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3 GRIN2B DEE27, EIEE27, GluN2B, MRD6, NMDAR2B, NR2B, NR3, hNR3 glutamate ionotropic receptor NMDA type subunit 2B glutamate receptor ionotropic, NMDA 2B|N-methyl D-aspartate receptor subtype 2B|N-methyl-D-aspartate receptor subunit 3|glutamate [NMDA] receptor subunit epsilon-2|glutamate receptor subunit epsilon-2|glutamate receptor, ionotropic, N-methyl D-aspartate 2B*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
For more info on GRIN2B, check out the GRIN2B Infographic
We have 30,000+ of these available, one for each gene! check them out.
In this infographic you will see the following information for GRIN2B: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]
No publications found for PA1059
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