Product Info Summary
SKU: | A02597S577 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-Phospho-B-Myb (S577) MYBL2 Antibody
SKU/Catalog Number
A02597S577
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-B-Myb (S577) MYBL2 Antibody catalog # A02597S577. Tested in ELISA, IF, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-B-Myb (S577) MYBL2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02597S577)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human B-Myb around the phosphorylation site of S577.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02597S577 is reactive to MYBL2 in Human, Mouse, Rat
Applications
A02597S577 is guaranteed for ELISA, IF, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
78.764kDa
Background of B-Myb
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.
Tsai L.-H., Nature 371:419-423(1994).
Patrick G.N., Nature 402:615-622(1999).
Kesavapany S., J. Neurosci. 24:4421-4431(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For MYBL2 (Source: Uniprot.org, NCBI)
Gene Name
MYBL2
Full Name
Myb-related protein B
Weight
78.764kDa
Alternative Names
B-MYB; BMYBMGC15600; Myb-like protein 2; myb-related protein B; v-myb avian myeloblastosis viral oncogene homolog-like 2; v-myb myeloblastosis viral oncogene homolog (avian)-like 2 MYBL2 B-MYB, BMYB MYB proto-oncogene like 2 myb-related protein B|myb-like protein 2|v-myb avian myeloblastosis viral oncogene homolog-like 2|v-myb myeloblastosis viral oncogene homolog-like 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MYBL2, check out the MYBL2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MYBL2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-B-Myb (S577) MYBL2 Antibody (A02597S577)
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No publications found for A02597S577
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