Anti-Phospho-Tau (T231) MAPT Rabbit Monoclonal Antibody

Boster Bio Anti-Phospho-Tau (T231) MAPT Rabbit Monoclonal Antibody catalog # P00097-1. Tested in IP, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 6 publication(s).

Product Info Summary

SKU: P00097-1
Size: 100 μl
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IP, IHC, WB

Product Name

Anti-Phospho-Tau (T231) MAPT Rabbit Monoclonal Antibody

See all Tau products

SKU/Catalog Number

P00097-1

Size

100 μl

Form

Liquid

Description

Boster Bio Anti-Phospho-Tau (T231) MAPT Rabbit Monoclonal Antibody catalog # P00097-1. Tested in IP, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Phospho-Tau (T231) MAPT Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # P00097-1)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

EIH-13

Immunogen

A synthesized peptide derived from human Phospho-Tau (T231)

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

P00097-1 is reactive to MAPT in Human, Mouse, Rat

Applications

P00097-1 is guaranteed for IP, IHC, WB Boster Guarantee

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive your next antibody/ELISA kit free of charge! Applicable to all scientists world wide.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:50-1:200
IP 1:50

Validation Images & Assay Conditions

Gene/Protein Information For MAPT (Source: Uniprot.Org, NCBI)

Uniprot ID

P10636

Gene ID

4137

Gene Name

MAPT

Full Name

Microtubule-associated protein tau

Weight

78.928kDa

Alternative Names

DDPAC; FLJ31424; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPT; MGC138549; microtubule-associated protein tau; MSTD; MSTDMAPTL; MTBT1; MTBT1Neurofibrillary tangle protein; MTBT2; Neurofibrillary tangle protein; PHF-tau; PPND; Tau; TAUPaired helical filament-tau MAPT DDPAC, FTDP-17L, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, tau-40, MAPT microtubule associated protein tau microtubule-associated protein tau|G protein beta1/gamma2 subunit-interacting factor 1|PHF-tau|neurofibrillary tangle protein|paired helical filament-tau|protein phosphatase 1, regulatory subunit 103

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on MAPT, check out the MAPT Infographic

MAPT infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for MAPT: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

P00097-1 has been cited in 6 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Micro-RNA-137 Inhibits Tau Hyperphosphorylation in Alzheimer's Disease and Targets the CACNA1C Gene in Transgenic Mice and Human Neuroblastoma %u2026

The expression of insulin-like growth factor-1 in senior patients with diabetes and dementia

Panax notoginsenoside Rb1 ameliorates Alzheimer?s disease by upregulating brain-derived neurotrophic factor and downregulating Tau protein expression

Chen C, Gu J, Basurto-Islas G, Jin N, Wu F, Gong CX, Iqbal K, Liu F. Sci Rep. 2017 Oct 18;7(1):13478. doi: 10.1038/s41598-017-13791-5. Up-regulation of casein kinase 1ε is involved in tau pathogenesis in Alzheimer’s disease

Han F1, Zhuang TT1, Chen JJ1, Zhu XL1,2, Cai YF1, Lu YP1. PLoS One. 2017 Sep 21;12(9):e0185102. doi: 10.1371/journal.pone.0185102. eCollection 2017. Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal ...

Li X, Li M, Li Y, Quan Q, Wang J. Neural Regen Res. 2012 Dec 25;7(36):2860-6. Doi: 10.3969/J.Issn.1673-5374.2012.36.002. Cellular And Molecular Mechanisms Underlying The Action Of Ginsenoside Rg1 Against Alzheimer'S Disease.

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4 Customer Q&As for Anti-Phospho-Tau (T231) MAPT Rabbit Monoclonal Antibody

Question

Our lab were satisfied with the WB result of your anti-Phospho-Tau (T231) Rabbit Monoclonal antibody. However we have seen positive staining in cervix carcinoma erythroleukemia cytoplasm using this antibody. Is that expected? Could you tell me where is MAPT supposed to be expressed?

Verified Customer

Verified customer

Asked: 2020-04-21

Answer

According to literature, cervix carcinoma erythroleukemia does express MAPT. Generally MAPT expresses in cytoplasm, cytosol. Regarding which tissues have MAPT expression, here are a few articles citing expression in various tissues:
Brain, Pubmed ID: 1512244, 2484340, 2495000, 2498079, 3131773, 15489334
Cervix carcinoma, Pubmed ID: 16964243, 18220336, 20068231
Cervix carcinoma, and Erythroleukemia, Pubmed ID: 23186163
Fetal brain, Pubmed ID: 2516729
Fetal brain cortex, Pubmed ID: 16443603
Leukemic T-cell, Pubmed ID: 19690332
Liver, Pubmed ID: 24275569

Boster Scientific Support

Answered: 2020-04-21

Question

We have seen staining in human fetal brain cortex. What should we do? Is anti-Phospho-Tau (T231) Rabbit Monoclonal antibody supposed to stain fetal brain cortex positively?

Verified Customer

Verified customer

Asked: 2020-01-03

Answer

According to literature fetal brain cortex does express MAPT. According to Uniprot.org, MAPT is expressed in parietal lobe, brain, fetal brain, fetal brain cortex, cervix carcinoma, leukemic t-cell, cervix carcinoma erythroleukemia, liver, among other tissues. Regarding which tissues have MAPT expression, here are a few articles citing expression in various tissues:
Brain, Pubmed ID: 1512244, 2484340, 2495000, 2498079, 3131773, 15489334
Cervix carcinoma, Pubmed ID: 16964243, 18220336, 20068231
Cervix carcinoma, and Erythroleukemia, Pubmed ID: 23186163
Fetal brain, Pubmed ID: 2516729
Fetal brain cortex, Pubmed ID: 16443603
Leukemic T-cell, Pubmed ID: 19690332
Liver, Pubmed ID: 24275569

Boster Scientific Support

Answered: 2020-01-03

Question

We are currently using anti-Phospho-Tau (T231) Rabbit Monoclonal antibody P00097-1 for mouse tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on primate tissues as well?

Verified Customer

Verified customer

Asked: 2019-09-09

Answer

The anti-Phospho-Tau (T231) Rabbit Monoclonal antibody (P00097-1) has not been tested for cross reactivity specifically with primate tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in primate you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-09-09

Question

We bought anti-Phospho-Tau (T231) Rabbit Monoclonal antibody for IP on brain a few months ago. I am using rat, and We intend to use the antibody for WB next. I am interested in examining brain as well as fetal brain in our next experiment. Could give a recommendation on which antibody would work the best for WB?

Verified Customer

Verified customer

Asked: 2017-09-07

Answer

I looked at the website and datasheets of our anti-Phospho-Tau (T231) Rabbit Monoclonal antibody and it seems that P00097-1 has been tested on rat in both IP and WB. Thus P00097-1 should work for your application. Our Boster satisfaction guarantee will cover this product for WB in rat even if the specific tissue type has not been validated. We do have a comprehensive range of products for WB detection and you can check out our website bosterbio.com to find out more information about them.

Boster Scientific Support

Answered: 2017-09-07

Size

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Ships directly to USA and Canada. For other regions, visit our distributors page

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P00097-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$299.00

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