Many biological assays use antibodies to detect MAPT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAPT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAPT antibodies...
We validate the specificity of these antibodies to MAPT by testing them on tissues known to express MAPT positively and negatively. Browse below to find the MAPT antibody that suites your experiment. We have 54 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Designing a Western blot for MAPT?
The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
DDPAC; FLJ31424; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPT; MGC138549; microtubule-associated protein tau; MSTD; MSTDMAPTL; MTBT1; MTBT1Neurofibrillary tangle protein; MTBT2; Neurofibrillary tangle protein; PHF-tau; PPND; Tau; TAUPaired helical filament-tau
Molecular Weight
Mass (kDA): 78.928 kDA
Genomic Context
Human
Location:
17q21.31
Sequence:
17; NC_000017.11 (45894382..46028334)
Tissue Specificity
Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
Subcellular Localizations
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
Diseases
Alzheimer's Disease
Dementia
Frontotemporal Dementia
Neurodegenerative Disorders
Tauopathies
Neurofibrillary Tangles
Secondary Parkinson Disease
Nerve Degeneration
Parkinson Disease
Progressive Supranuclear Palsy
Supranuclear Palsy
Frontotemporal Lobar Degeneration
Atrophy
Impaired Cognition
Corticobasal Degeneration
Pick Disease Of The Brain
Plaque, Amyloid
Cognition Disorders
Senile Plaques
Interacting Proteins
AKT1
ANXA2
ANXA6
APOE
APP
DCTN1
DDX6
FKBP5
FYN
GSK3B
HSP90AB1
HSPA8
HTRA1
LRRK2
MAPRE3
MARK2
PRNP
RPL28
SFN
SLC1A2
SNCA
STUB1
YWHAZ
Pathways
Pathogenesis
Hyperphosphorylation
Aging
Transport
Cell Death
Localization
Proteolysis
Secretion
Cognition
Cell Cycle
Mrna Splicing
Translation
Autophagy
Protein Phosphorylation
Neurogenesis
Methylation
Dna Methylation
Mitosis
Locomotion
Rna Interference
PTMs
Phosphorylation
Cleavage
Dephosphorylation
Ubiquitination
Reduction
Acetylation
Methylation
Sulphation
Deamination
Amidation
Gamma-cleavage
Biotinylation
Deacetylation
Glycosylation
Research Areas
Alzheimers Research
Apoptosis
Cell Biology
Cellular Markers
Cytokine Research
MAP Kinase Signaling
Neurodegeneration
Neuroscience
Phospho-Specific
Stem Cell Markers
For details, visit: bosterbio.com/bosterbio-gene-info-cards/MAPT
References
PMID: 3131773 by Goedert M., et al. Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.
PMID: 2498079 by Goedert M., et al. Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.
10 Publications of Boster MAPT Antibodies & ELISA Kits
PubMed ID: 10.1007/s00277-008-0470-3, Simultaneous expression of Oct4 and genes of three germ layers in single cell-de...