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- Table of Contents
ORAI3 antibody (A09399) performs well in ELISA, IHC-P, ICC, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 1 Publication
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Immunohistochemistry of ORAI3 in mouse spleen tissue with ORAI3 antibody at 2 μg/mL.
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Anti-Protein orai-3 ORAI3 Antibody
ORAI3 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | ELISA, IHC-P, ICC, WB |
Recommend Dilution
Application
Dilution
Species
ORAI3 antibody can be used for detection of ORAI3 by Western blot at 1 - 4 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL and Immunohistochemistry starting at 2 μg/mL
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-Protein orai-3 ORAI3 Antibody
View all ORAI3 Antibodies
View all ORAI3 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
ORAI3 antibody can be stored at 4°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Rabbit
Contents
ORAI3 Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ORAI3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human ORAI3. The immunogen is located within the first 50 amino acids of ORAI3.
Cross-Reactivity
This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
31.5 kDa
Background of ORAI3
Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter.
Cite This Product
Anti-Protein orai-3 ORAI3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09399)
Publications
Application:
Species:
The calcium channel proteins ORAI3 and STIM1 mediate TGF-β induced Snai1 expression
Published: 2018-06-29
Journal: Oncotarget
Application: WB
Impact Factor: 0.00
Species: Human
PMID: 30034631
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Product Promise
We promise Anti-Protein orai-3 ORAI3 Antibody performs excellently in relevant applications for ELISA, IHC-P, ICC, WB. If it doesn't perform as promised, we will refund the product. Learn more
In stock
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A09399
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
Troubleshooting
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 9, 2026