Anti-RAIDD CRADD Antibody

RAIDD/CRADD antibody

Boster Bio Anti-RAIDD CRADD Antibody catalog # A06509-2. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A06509-2
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-RAIDD CRADD Antibody

View all RAIDD/CRADD Antibodies

SKU/Catalog Number

A06509-2

Size

100ul

Form

Liquid

Description

Boster Bio Anti-RAIDD CRADD Antibody catalog # A06509-2. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-RAIDD CRADD Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06509-2)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human BCL2L12

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A06509-2 is reactive to CRADD in Human, Mouse, Rat

Applications

A06509-2 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

22.745kDa

Background of RAIDD/CRADD

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.

Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436].
Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258].
Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983].

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000

Validation Images & Assay Conditions

Gene/Protein Information For CRADD (Source: Uniprot.org, NCBI)

Gene Name

CRADD

Full Name

Death domain-containing protein CRADD

Weight

22.745kDa

Alternative Names

CASP2 and RIPK1 domain containing adaptor with death domain; Caspase and RIP adapter with death domain; caspase and RIP adaptor with death domain; CRADD; death domain containing protein CRADD; death domain-containing protein CRADD; MGC9163; RAIDD; RAIDDdeath adaptor molecule RAIDD; RIP-associated ICH1/CED3-homologous protein with death domain; RIP-associated protein with a death domain CRADD MRT34, RAIDD CASP2 and RIPK1 domain containing adaptor with death domain death domain-containing protein CRADD|CRADD/LYZ fusion|RIP-associated ICH1/CED3-homologous protein with death domain|caspase and RIP adaptor with death domain|death adaptor molecule RAIDD|death domain containing protein CRADD

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CRADD, check out the CRADD Infographic

CRADD infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CRADD: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A06509-2-100ul

100ul

$405

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