Product Info Summary
SKU: | A06509-2 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-RAIDD CRADD Antibody
View all RAIDD/CRADD Antibodies
SKU/Catalog Number
A06509-2
Size
100ul
Form
Liquid
Description
Boster Bio Anti-RAIDD CRADD Antibody catalog # A06509-2. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-RAIDD CRADD Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06509-2)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human BCL2L12
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A06509-2 is reactive to CRADD in Human, Mouse, Rat
Applications
A06509-2 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
22.745kDa
Background of RAIDD/CRADD
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.
Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436].
Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258].
Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983].
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-RAIDD CRADD Antibody A06509-2
Western blot (WB) analysis of RAIDD polyclonal antibody at 1:500 dilutionLane1:MCF-7 whole cell lysate
Lane2:sp2/0 whole cell lysate
Lane3:PC12 whole cell lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For CRADD (Source: Uniprot.org, NCBI)
Gene Name
CRADD
Full Name
Death domain-containing protein CRADD
Weight
22.745kDa
Alternative Names
CASP2 and RIPK1 domain containing adaptor with death domain; Caspase and RIP adapter with death domain; caspase and RIP adaptor with death domain; CRADD; death domain containing protein CRADD; death domain-containing protein CRADD; MGC9163; RAIDD; RAIDDdeath adaptor molecule RAIDD; RIP-associated ICH1/CED3-homologous protein with death domain; RIP-associated protein with a death domain CRADD MRT34, RAIDD CASP2 and RIPK1 domain containing adaptor with death domain death domain-containing protein CRADD|CRADD/LYZ fusion|RIP-associated ICH1/CED3-homologous protein with death domain|caspase and RIP adaptor with death domain|death adaptor molecule RAIDD|death domain containing protein CRADD
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CRADD, check out the CRADD Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CRADD: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-RAIDD CRADD Antibody (A06509-2)
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No publications found for A06509-2
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