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Product Info Summary
| SKU: | M00433-3 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Mouse |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-SirT2 Monoclonal Antibody
SKU/Catalog Number
M00433-3
Size
100ul
Form
Liquid
Description
Boster Bio Anti-SirT2 Monoclonal Antibody catalog # M00433-3. Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SirT2 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00433-3)
Host
Mouse
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Monoclonal
Clone Number
1D4-H11-H11
Isotype
IgG
Immunogen
Purified recombinant human SirT2 protein expressed in E.coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00433-3 is reactive to SIRT2 in Human, Mouse, Rat
Applications
M00433-3 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
43.182kDa
Background of SIRT2
Paired box protein Pax-6 also known as aniridia type II protein (AN2) or oculorhombin is a transcription factor with key functions in the development of the eye, nose, central nervous system and pancreas. Pax6 further seems to be required for the differentiation of pancreatic islet alpha cells. PAX6 has been shown to bind to a promoter element in the glucagon, insulin and somatostatin promoters and regulates the specification of the ventral neuron subtypes by establishing the correct progenitor domains. Isoform 5a appears to function as a molecular switch that specifies target genes. Anti-PAX6 antibody is ideal for researchers interested in developmental biology, stem cell research, cell growth and cancer research.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-2000
ELISA 1:10000-20000
Validation Images & Assay Conditions
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Figure 2. Immunofluorescent staining data of SIRT2 using Anti-SirT2 Monoclonal Antibody (M00433-3).
Immunofluorescent analysis of Hela cells fixed by anhydrous methanol at -20°C and using SirT2 (200474
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Figure 1. Western blotting validation for Anti-SirT2 Monoclonal Antibody M00433-3
Western blot detection of SirT2 in PC-12Protein Target Info & Infographic
Gene/Protein Information For SIRT2 (Source: Uniprot.org, NCBI)
Gene Name
SIRT2
Full Name
NAD-dependent protein deacetylase sirtuin-2
Weight
43.182kDa
Superfamily
sirtuin family
Alternative Names
EC 3.5.1; EC 3.5.1.-; FLJ35621; FLJ37491; S.cerevisiae, homolog) 2; sirtuin 2; sirtuin type 2 SIRT2 SIR2, SIR2L, SIR2L2 sirtuin 2 NAD-dependent protein deacetylase sirtuin-2|NAD-dependent deacetylase sirtuin-2|SIR2-like protein 2|regulatory protein SIR2 homolog 2|silent information regulator 2|sir2-related protein type 2|sirtuin type 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SIRT2, check out the SIRT2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SIRT2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SirT2 Monoclonal Antibody (M00433-3)
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No publications found for M00433-3
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Customer Reviews
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