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Product Info Summary
| SKU: | A03988 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SLAMF1 Antibody
SKU/Catalog Number
A03988
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SLAMF1 Antibody (Catalog # A03988). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SLAMF1 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SLAMF1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03988)
Host
Rabbit
Contents
SLAMF1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SLAMF1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SLAMF1. The immunogen is located within amino acids 30 - 80 of SLAMF1.
Cross-reactivity
4 isoforms of SLAMF1 are known to exist; this antibody will is predicted to recognize all 4 isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members.
Reactive Species
A03988 is reactive to SLAMF1 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
37.2 kDa
Background of SLAMF1
The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03988 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SLAMF1 antibody can be used for detection of SLAMF1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SLAMF1 in rat colon tissue lysate with SLAMF1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of SLAMF1 in human colon tissue with SLAMF1 antibody at 5 μg/mL.
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Immunofluorescence of SLAMF1 in human colon tissue with SLAMF1 antibody at 20 μg/mL.
Specific Publications For Anti-SLAMF1 Antibody (A03988)
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