Anti-Synapsin II/SYN2 Antibody Picoband™

Synapsin II antibody

Boster Bio Anti-Synapsin II/SYN2 Antibody Picoband™ catalog # PB10100. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: PB10100
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-Synapsin II/SYN2 Antibody Picoband™

View all Synapsin II Antibodies

SKU/Catalog Number

PB10100

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Synapsin II/SYN2 Antibody Picoband™ catalog # PB10100. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Synapsin II/SYN2 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB10100)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived human Synapsin II recombinant protein (Position: A497-D582). Human Synapsin II shares 93.1% and 89.7% amino acid (aa) sequence identity with mouse and rat Synapsin II, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

PB10100 is reactive to SYN2 in Human, Mouse, Rat

Applications

PB10100 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

52, 70 kDa

Calculated molecular weight

62.996kDa

Background of Synapsin II

Synapsin II is the collective name for synapsin IIa and synapsin IIb, two nearly identical phosphoproteins in the synapsin family that in humans are encoded by the SYN2 gene. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite direction.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For SYN2 (Source: Uniprot.org, NCBI)

Gene Name

SYN2

Full Name

Synapsin-2

Weight

62.996kDa

Superfamily

synapsin family

Alternative Names

synapsin IISYNII; synapsin-2; SYNIIa; SYNIIb SYN2 SYNII synapsin II synapsin-2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SYN2, check out the SYN2 Infographic

SYN2 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SYN2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB10100 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Fei Y,Zhao B,Zhu J,Fang W,Li Y.XQ-1H promotes cerebral angiogenesis via activating PI3K/Akt/GSK3β/β-catenin/VEGF signal in mice exposed to cerebral ischemic injury.Life Sci.2021 Feb 16:119234.doi:10.1016/j.lfs.2021.119234.Epub ahead of print.PMID:33607158
Species: Human,Mouse
PB10100 usage in article: APP:WB, SAMPLE:BRAIN CORTEX, DILUTION:NA

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5 Customer Q&As for Anti-Synapsin II/SYN2 Antibody Picoband™

Question

We are currently using anti-Synapsin II/SYN2 antibody PB10100 for rat tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on pig tissues as well?

Verified Customer

Verified customer

Asked: 2019-07-11

Answer

The anti-Synapsin II/SYN2 antibody (PB10100) has not been validated for cross reactivity specifically with pig tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-07-11

Question

Is there a BSA free version of anti-Synapsin II/SYN2 antibody PB10100 available?

Verified Customer

Verified customer

Asked: 2018-11-05

Answer

I appreciate your recent telephone inquiry. I can confirm that some lots of this anti-Synapsin II/SYN2 antibody PB10100 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.

Boster Scientific Support

Answered: 2018-11-05

Question

I see that the anti-Synapsin II/SYN2 antibody PB10100 works with WB, what is the protocol used to produce the result images on the product page?

Verified Customer

Verified customer

Asked: 2018-04-09

Answer

You can find protocols for WB on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2018-04-09

Question

Does anti-Synapsin II/SYN2 antibody PB10100 work for WB with middle temporal gyrus?

Verified Customer

Verified customer

Asked: 2017-06-06

Answer

According to the expression profile of middle temporal gyrus, SYN2 is highly expressed in middle temporal gyrus. So, it is likely that anti-Synapsin II/SYN2 antibody PB10100 will work for WB with middle temporal gyrus.

Boster Scientific Support

Answered: 2017-06-06

Question

My question regarding product PB10100, anti-Synapsin II/SYN2 antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?

Z. Carter

Verified customer

Asked: 2015-05-25

Answer

We suggest not storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free PB10100 anti-Synapsin II/SYN2 antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.

Boster Scientific Support

Answered: 2015-05-25

Order DetailsPrice
PB10100

100μg

$370
PB10100-10ug

10μg sample (liquid)

$99
PB10100-Biotin

100 μg Biotin conjugated

$570
PB10100-Cy3

100 μg Cy3 conjugated

$570
PB10100-Dylight488

100 μg Dylight488 conjugated

$570
PB10100-Dylight550

100 μg Dylight550 conjugated

$570
PB10100-Dylight594

100 μg Dylight594 conjugated

$570
PB10100-FITC

100 μg FITC conjugated

$570
PB10100-HRP

100 μg HRP conjugated

$570
PB10100-APC

100 μg APC conjugated

$670
PB10100-PE

100 μg PE conjugated

$670
PB10100-carrier-free

Carrier Free

$370

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PB10100
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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