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Product Info Summary
| SKU: | A00803 |
|---|---|
| Size: | 100μl |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | WB |
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Product info
Product Name
Anti-TBX5 Monoclonal Antibody
SKU/Catalog Number
A00803
Size
100μl
Form
Liquid
Description
Boster Bio Anti-TBX5 Monoclonal Antibody catalog # A00803. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TBX5 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00803)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
7B11
Isotype
IgG
Immunogen
Purified recombinant fragment of TBX5 expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00803 is reactive to TBX5 in Human
Applications
A00803 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
57.711kDa
Background of TBX5
Signaling adapter that couples activated growth factor receptors to signaling pathway. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span
Trampont P, et al. (2006) Mol Cell Biol; 26(23): 9035-9044.
Patrussi L, et al. (2005) Oncogene; 24(13): 2218-2228
van der Geer P, et al. (1996) Curr Biol ; 6(11): 1435-1444
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
Validation Images & Assay Conditions
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Western Blot (WB) analysis using TBX5 Monoclonal antibody against HepG2 cell lysate (1).
Protein Target Info & Infographic
Gene/Protein Information For TBX5 (Source: Uniprot.org, NCBI)
Gene Name
TBX5
Full Name
T-box transcription factor TBX5
Weight
57.711kDa
Alternative Names
HOS; T-box 5; T-box protein 5; T-box transcription factor TBX5; TBX5 TBX5 HOS T-box transcription factor 5 T-box transcription factor TBX5|T-box 5|T-box protein 5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TBX5, check out the TBX5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TBX5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TBX5 Monoclonal Antibody (A00803)
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No publications found for A00803
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Customer Reviews
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