Product Info Summary
SKU: | A02808-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Myosin-6 MYH6 Antibody
SKU/Catalog Number
A02808-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Myosin-6 MYH6 Antibody catalog # A02808-1. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Myosin-6 MYH6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02808-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human PIAS3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02808-1 is reactive to MYH6 in Human, Mouse, Rat
Applications
A02808-1 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
223.735kDa
Background of MYH6
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.
Jiang-Hong Man, Nucleic Acids Res., Nov 2006; 34: 5552 - 5566.
Amir Sonnenblick, Mol. Cell. Biol., Dec 2004; 24: 10584 - 10592.
Jianyin Long, PNAS, Jan 2004; 101: 99.
Hyun Duk Jang, J. Biol. Chem., Jun 2004; 279: 24873 - 24880.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1,000-1:2,000
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of MYH6 using Anti-Myosin-6 MYH6 Antibody (A02808-1).
Immunohistochemical analysis of paraffin-embedded mouse smooth muscle tissue using anti-Myosin heavy chain antibody. Counter stained with hematoxylin.For more protocol information of IHC
Click image to see more details
Figure 1. Western blotting validation for Anti-Myosin-6 MYH6 Antibody A02808-1
Western blot analysis of Myosin heavy chain on human skeletal muscle lysates using anti-Myosin heavy chain antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For MYH6 (Source: Uniprot.org, NCBI)
Gene Name
MYH6
Full Name
Myosin-6
Weight
223.735kDa
Superfamily
TRAFAC class myosin-kinesin ATPase superfamily
Alternative Names
alpha-MHC; ASD3; cardiomyopathy; CMD1EE; CMH14; Hypertrophic 1; MYH6; MYHC; MYHCA; MyHC-Alpha; Myosin Heavy Chain 6; Myosin Heavy Chain, Cardiac Muscle Alpha Isoform; Myosin, Heavy Chain 6, Cardiac Muscle, Alpha; Myosin, Heavy Polypeptide 6, Cardiac Muscle, Alpha (Cardiomyopathy, Hypertrophic 1); Myosin-6; SSS3 MYH6 ASD3, CMD1EE, CMH14, MYHC, MYHCA, SSS3, alpha-MHC myosin heavy chain 6 myosin-6|myHC-alpha|myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MYH6, check out the MYH6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MYH6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Myosin-6 MYH6 Antibody (A02808-1)
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No publications found for A02808-1
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Customer Q&As
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1 Customer Q&As for Anti-Myosin-6 MYH6 Antibody
Question
Does A02808-1 cross react with MYH7(Myosin heavy chain beta) for WB or IF?
Verified customer
Asked: 2021-02-21
Answer
The Anti-Myosin-6 MYH6 Antibody (A02808-1) cross reacts with MYH7and not suitable for IF.
Boster Scientific Support
Answered: 2021-02-23