Anti-TRPC6 Antibody

Boster Bio Anti-TRPC6 Antibody catalog # PA1754. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 3 publication(s).

Product Info Summary

SKU: PA1754
Size: 100μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-TRPC6 Antibody

See all TRPC6 products

SKU/Catalog Number

PA1754

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-TRPC6 Antibody catalog # PA1754. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TRPC6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1754)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human TRPC6 (249-265aa HDYFCKCNDCNQKQKHD), different from the related rat and mouse sequences by three amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PA1754 is reactive to TRPC6 in Human, Mouse, Rat

Applications

PA1754 is guaranteed for IHC, WB Boster Guarantee

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For TRPC6 (Source: Uniprot.Org, NCBI)

Uniprot ID

Q9Y210

Gene ID

7225

Gene Name

TRPC6

Full Name

Short transient receptor potential channel 6

Weight

106.326kDa

Superfamily

transient receptor (TC 1.A.4) family

Alternative Names

FLJ11098; FSGS2; short transient receptor potential channel 6; transient receptor potential cation channel, subfamily C, member 6; Transient receptor protein 6; TRP-6; TRP6FLJ14863; TrpC6 TRPC6 FSGS2, TRP6 transient receptor potential cation channel subfamily C member 6 short transient receptor potential channel 6|TRP-6|focal segmental glomerulosclerosis 2|transient receptor protein 6

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on TRPC6, check out the TRPC6 Infographic

TRPC6 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for TRPC6: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

PA1754 has been cited in 3 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Wang Y,Liu L,Tao H,Wen L,Qin S.TRPC6 participates in the development of blood pressure variability increase in sino-aortic denervated rats. Heart Vessels. 2020 Dec;35(12):1755-1765.doi: 10.1007/s00380-020-01682-1.Epub 2020 Aug 25.PMID: 32844288.
Species: Rat
PA1754 usage in article: APP:IF, SAMPLE:MYOCARDIAL AND THORACIC AORTIC TISSUE, DILUTION:1:50

TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells

Sun Yh, Li Yq, Feng Sl, Li Bx, Pan Zw, Xu Cq, Li Tt, Yang Bf. Biochem Biophys Res Commun. 2010 Apr 16;394(4):955-61. Doi: 10.1016/J.Bbrc.2010.03.096. Epub 2010 Mar 20. Calcium-Sensing Receptor Activation Contributed To Apoptosis Stimulates Trpc6 C...

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1 Customer Q&As for Anti-TRPC6 Antibody

Question

We are currently using anti-TRPC6 antibody PA1754 for rat tissue, and we are well pleased with the IHC results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on goat tissues as well?

Verified Customer

Verified customer

Asked: 2017-06-20

Answer

The anti-TRPC6 antibody (PA1754) has not been tested for cross reactivity specifically with goat tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in goat you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2017-06-20

Size

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Ships directly to USA and Canada. For other regions, visit our distributors page

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PA1754
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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