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- Table of Contents
ALOX5 Antibodies
AND ALOX5 ELISA kits, ALOX5 Proteins
Many biological assays use antibodies to detect ALOX5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ALOX5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ALOX5 antibodies...
Designing a Western blot for ALOX5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ALOX5 Western Blot GuideALOX5 Infographic by Boster Bio
All ALOX5 Products
Product
Figures
Specificity
Applications
Price
Anti-5 Lipoxygenase/ALOX5 Antibody Picoband®
2 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # RP1031
100 μg/vial
Cat # RP1031
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02341
100 μg/vial
Cat # A02341
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00847
100 μl
Cat # M00847
100 μl
Human, Mouse, Rat
ELISA
$540
Cat # EKC2187
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2187
1 kit, containing two 96-well plates and all necessary reagents
Human
$960
Cat # LS000240
20 µg, 100 µg
Cat # LS000240
20 µg, 100 µg
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00847S272
100ul
Cat # A00847S272
100ul
ALOX5 Overview
Facts about Arachidonate 5-lipoxygenase.
Arachidonate 5-lipoxygenase (ALOX5)
Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ALOX5 |
| Uniprot: | P09917 |
| Entrez: | 240 |
Family
| Belongs to: |
|---|
| lipoxygenase family |
Alternative Names
5Lipoxygenase; 5-Lipoxygenase; 5-LO; 5-LOX; 5LPG; ALOX5; arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; EC 1.13.11; EC 1.13.11.34; leukotriene A4 synthase; LOG5; LOX5A; MGC163204
Molecular Weight
Mass (kDA):
77.983 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q11.21 |
| Sequence: | 10; NC_000010.11 (45374166..45446121) |
Subcellular Localizations
Cytoplasm. Nucleus matrix. Nucleus membrane; Peripheral membrane protein. Shuttles between cytoplasm and nucleus. Found exclusively in the nucleus, when phosphorylated on Ser-272. Calcium binding promotes translocation from the cytosol and the nuclear matrix to the nuclear envelope and membrane association.
Diseases
- Asthma
- Inflammation
- Malignant Neoplasms
- Atherosclerosis
- Myeloid Leukemia
- Leukemia
- Neoplasms
- Cardiovascular Diseases
- Myeloid Leukemia, Chronic
- Dysequilibrium Syndrome
- Infarction
- Rhinorrhea
- Myocardial Infarction
Interacting Proteins
- CEP63
- COTL1
- FGR
- GATC
- HCK
- HHIPL2
- MAD1L1
- MEOX1
- NUTM1
- PRKACA
Pathways
- Pathogenesis
- Secretion
- Cell Proliferation
- Rna Interference
- Hypersensitivity
- Cell Cycle
- Cell Death
- Lipoxygenase Pathway
- Angiogenesis
- Transport
- Gene Silencing
- Cellular Senescence
- Monocyte Chemotaxis
PTMs
Research Areas
- Cancer
- Cholesterol Metabolism
- Lipid and Metabolism
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ALOX5
bosterbio.com/bosterbio-gene-info-cards/ALOX5
References
PMID: 3422434 by Dixon R.A.F., et al. Cloning of the cDNA for human 5-lipoxygenase.
PMID: 2829172 by Matsumoto T., et al. Molecular cloning and amino acid sequence of human 5-lipoxygenase.