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- Table of Contents
ALPL Antibodies
AND ALPL ELISA kits, ALPL Proteins
Many biological assays use antibodies to detect ALPL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ALPL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ALPL antibodies...
Designing a Western blot for ALPL? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ALPL Western Blot GuideALPL Infographic by Boster Bio
All ALPL Products
Product
Figures
Specificity
Applications
Price
Human
IF, IHC, ICC, WB
$370
Cat # PA1004
100 μg/vial
Cat # PA1004
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01008-1
100 μl
Cat # M01008-1
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01008-1
100 μg/vial
Cat # A01008-1
100 μg/vial
Human, Mouse, Rat
ELISA, IF, ICC, WB
$370
Cat # A01008
100 μg/vial
Cat # A01008
100 μg/vial
Human
$628
Cat # LS000249
20 µg, 100 µg
Cat # LS000249
20 µg, 100 µg
Enzyme Activity, SDS-PAGE
$265
Cat # PROTP09242
Starting from 10ug
Cat # PROTP09242
Starting from 10ug
Enzyme Activity, SDS-PAGE
$300
Cat # PROTP05186
Starting from 10ug
Cat # PROTP05186
Starting from 10ug
ALPL Overview
Facts about Alkaline phosphatase, tissue-nonspecific isozyme.
Alkaline phosphatase, tissue-nonspecific isozyme (ALPL)
This isozyme may play a role in skeletal mineralization. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ALPL |
| Uniprot: | P05186 |
| Entrez: | 249 |
Family
| Belongs to: |
|---|
| alkaline phosphatase family |
Alternative Names
Akp2; Alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase, liver/bone/kidney; alkaline phosphatase, tissue-nonspecific isozyme; alkaline phosphomonoesterase; ALPL; APTNAP; AP-TNAP; EC 3.1.3.1; FLJ40094; FLJ93059; glycerophosphatase; HOPS; liver/bone/kidney-type alkaline phosphatase; MGC161443; tissue-nonspecific ALP; TNAP; TNSALP; TNSALPMGC167935
Molecular Weight
Mass (kDA):
57.305 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.12 |
| Sequence: | 1; NC_000001.11 (21508984..21578412) |
Subcellular Localizations
Cell membrane; Lipid-anchor, GPI-anchor.
Diseases
- Hypophosphatasia
- Hereditary Pyropoikilocytosis
- Neoplasms
- Meningioma
- Fracture
- Malignant Neoplasms
- Bone Diseases
- Osteoporosis
- Osteopenia
- Tooth Loss
- Meningeal Neoplasms
- Dysequilibrium Syndrome
Interacting Proteins
- MAP3K14
Pathways
- Bone Mineralization
- Regeneration
- Bone Resorption
- Osteoblast Differentiation
- Cell Differentiation
- Dentin Mineralization
- Ossification
- Pathogenesis
- Transport
- Tooth Mineralization
- Localization
- Methylation
- Enamel Mineralization
PTMs
- Methylation
- Sulphation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ALPL
bosterbio.com/bosterbio-gene-info-cards/ALPL
References
PMID: 3532105 by Weiss M.J., et al. Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphatase.
PMID: 3165380 by Weiss M.J., et al. Structure of the human liver/bone/kidney alkaline phosphatase gene.
29 Publications of Boster ALPL Antibodies & ELISA Kits
- PubMed ID: 10.1155/2019/2075968, Less Vertebral Bone Mass after Treatment with Macitentan in Mice: A Pilot Study
- PubMed ID: 10.1016/j.msec.2016.09.085, Preparation, physicochemical properties and biocompatibility of PBLG/PLGA/biogla...
- PubMed ID: 10.1002/ar.21036, Prevention of Osteoporosis in Mice after Ovariectomy via Allograft of Microencap...
- PubMed ID: 10.1002/ar.21036, Prevention of Osteoporosis in Mice after Ovariectomy via Allograft of Microencap...
- PubMed ID: 10.1002/ar.21036, Prevention of Osteoporosis in Mice after Ovariectomy via Allograft of Microencap...
- PubMed ID: -, Hou,C.,Wang,X.,Jiang,W.,Bian,Z.,Zhu,L.,& Li,M.(2021).Peptide 11R‑VIVIT promote...
- PubMed ID: 32018039, Chen G,Wang Q,Li Z,Yang Q,Liu Y,Du Z,Zhang G,Song Y.Circular RNA CDR1as promotes...
- PubMed ID: 32857019, Zhang Y,Yin C,Cheng Y,Huang X,Liu K,Cheng G,Li Z.Electrospinning Nanofiber-Reinf...
- PubMed ID: 29218094, (+)-Cholesten-3-one induces osteogenic differentiation of bone marrow mesenchyma...
- PubMed ID: 28797104, Zhang Y, Wei QS, Ding WB, Zhang LL, Wang HC, Zhu YJ, He W, Chai YN, Liu YW. PLoS...
- PubMed ID: 25657680, Liu B, Deng C, Zhang Y, Zhang J. Neural Regen Res. 2012 Jul 5;7(19):1463-8. Doi:...
- PubMed ID: 21270971, Su Y, Wang F, Qi H, Zhao Sg, Li X, Cui H. Mol Vis. 2011 Jan 22;17:247-56. Small ...
- PubMed ID: 20653335, Li Q, Xia Yy, Tang Jc, Wang Ry, Bei Cy, Zeng Y. Artif Cells Blood Substit Immobi...
- PubMed ID: 21289500, Zhao Jw, Gao Zl, Mei H, Li Yl, Wang Y. Am J Med Sci. 2011 Jun;341(6):460-8. Doi:...
- PubMed ID: 22179675, Zhang P, Wu X, Hu C, Wang P, Li X. In Vitro Cell Dev Biol Anim. 2012 Jan;48(1):3...
- PubMed ID: 21556124, Shen Z, Ren Y, Ye D, Guo J, Kang C, Ding H. Eur J Histochem. 2011 Mar 21;55(1):E...
- PubMed ID: 20646735, Lu Gh, Song Wt, Wang C, Yan Zh. Chemosphere. 2010 Aug;80(9):982-90. Doi: 10.1016...
- PubMed ID: 24300127, Shen Z, Zhan G, Deng H, Ren Y, Ye D, Xiao B, Guo J. J Laryngol Otol. 2013 Dec;12...
- PubMed ID: 24580816, Liu J, Lu G, Wu D, Yan Z. Ecotoxicol Environ Saf. 2014 Apr;102:12-7. Doi: 10.101...
- PubMed ID: 16814270, Li M, Yan Z, Han W, Zhang Y. Cell Immunol. 2006 Feb;239(2):136-43. Epub 2006 Jun...
- PubMed ID: 20075284, Guan W, Wang Y, Hou L, Chen L, Li X, Yue W, Ma Y. Poult Sci. 2010 Feb;89(2):312-...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page