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- Table of Contents
13 Citations 9 Q&As
14 Citations 11 Q&As
4 Citations 8 Q&As
2 Citations 1 Q&As
Facts about C-C motif chemokine 5.
May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells.
Human | |
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Gene Name: | CCL5 |
Uniprot: | P13501 |
Entrez: | 6352 |
Belongs to: |
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intercrine beta (chemokine CC) family |
CCL5; chemokine (C-C motif) ligand 5; D17S136Enormally T-expressed, and presumably secreted; EoCP; Eosinophil chemotactic cytokine; RANTES; SISd; SIS-delta; small inducible cytokine A5 (RANTES); small inducible cytokine subfamily A (Cys-Cys), member 5; Small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; TCP228T-cell-specific protein RANTES
Mass (kDA):
9.99 kDA
Human | |
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Location: | 17q12 |
Sequence: | 17; NC_000017.11 (35871491..35880360, complement) |
Expressed in the follicular fluid (at protein level). T-cell and macrophage specific.
Secreted.
PMID: 2456327 by Schall T.J., et al. A human T cell-specific molecule is a member of a new gene family.
PMID: 10213461 by Nomiyama H., et al. Organization of the chemokine gene cluster on human chromosome 17q11.2 containing the genes for CC chemokine MPIF-1, HCC-2, LEC, and RANTES.
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page