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- Table of Contents
CD14 Antibodies
AND CD14 ELISA kits, CD14 Proteins
Many biological assays use antibodies to detect CD14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD14 antibodies...
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CD14 Infographic by Boster Bio
All CD14 Products
Product
Figures
Specificity
Applications
Price
Mouse CD14 ELISA Kit PicoKine®
1 Citations 13 Q&As
Mouse
ELISA
$499
Cat # EK0695
96 wells/kit, with removable strips.
Cat # EK0695
96 wells/kit, with removable strips.
Anti-CD14 Rabbit Monoclonal Antibody
1 Citations 16 Q&As
Human
IF, IHC, ICC, WB
$370
Cat # M00137
100 μl
Cat # M00137
100 μl
Human CD14 ELISA Kit PicoKine®
1 Citations 7 Q&As
Human
ELISA
$499
Cat # EK0694
96 wells/kit, with removable strips.
Cat # EK0694
96 wells/kit, with removable strips.
Human
ELISA, Flow Cytometry, IHC-P
$304
Cat # M00137-1
0.1 mg
Cat # M00137-1
0.1 mg
Human
Flow Cytometry, IF, IHC-P, WB, IHC-P-Leica
$299
Cat # A00137-1
80 µl
Cat # A00137-1
80 µl
Anti-CD14 Antibody
4 Citations
Human
ELISA, Flow Cytometry, IF, IHC, ICC
$370
Cat # A00137-2
100 μg/vial
Cat # A00137-2
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00137-3
100 μg
Cat # M00137-3
100 μg
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00137-4
20μL, 40μL, 100μL, 200μL
Cat # M00137-4
20μL, 40μL, 100μL, 200μL
Human, Mouse
ELISA, IP, IF, IHC, WB
$146
Cat # M00137-5
20μL, 40μL, 100μL, 200μL
Cat # M00137-5
20μL, 40μL, 100μL, 200μL
CD14 Overview
Facts about Monocyte differentiation antigen CD14.
Monocyte differentiation antigen CD14 (CD14)
Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and provides it to the LY96/TLR4 complicated, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655).
Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters activate signaling from the cell surface and then are targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211).
Gene Information
| Human | |
|---|---|
| Gene Name: | CD14 |
| Uniprot: | P08571 |
| Entrez: | 929 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD14 antigen; CD14 molecule; CD14; monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein
Molecular Weight
Mass (kDA):
40.076 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q31.3 |
| Sequence: | 5; NC_000005.10 (140631728..140633701, complement) |
Tissue Specificity
Detected on macrophages (at protein level) (PubMed:1698311). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
Subcellular Localizations
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus. Secreted forms may arise by cleavage of the GPI anchor.
Diseases
- Inflammation
- Leukemia
- Tissue Adhesions
- Systemic Infection
- Inflammatory Response
- Infective Disorder
- Neoplasms
- Malignant Neoplasms
- Myeloid Leukemia
- Leukemia, Myelocytic, Acute
- Hiv Infections
- Septic Shock
- Asthma
Interacting Proteins
- FSTL1
Pathways
- Secretion
- Immune Response
- Pathogenesis
- Cytokine Production
- Inflammatory Response
- Cell Activation
- Phagocytosis
- Cell Differentiation
- Cell Proliferation
- Innate Immune Response
- Cell Adhesion
- Cell Cycle
- Cell Death
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
- Acetylation
- Methylation
- Reduction
- Dephosphorylation
- Biotinylation
- Nitration
- Acylation
Research Areas
- Apoptosis
- Asthma
- Cancer
- Cell Biology
- Immunology
- Innate Immunity
- Myeloid Cell Markers
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD14
bosterbio.com/bosterbio-gene-info-cards/CD14
References
PMID: 3385210 by Haziot A., et al. The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage.
PMID: 2453848 by Ferrero E., et al. Nucleotide sequence of the gene encoding the monocyte differentiation antigen, CD14.
13 Publications of Boster CD14 Antibodies & ELISA Kits
- PubMed ID: 10.3892/ol.2012.981, Expression and clinical significance of extracellular matrix metalloproteinase i...
- PubMed ID: 10.3390/nu11123004, The Effect of Hops (Humulus lupulus L.) Extract Supplementation on Weight Gain, ...
- PubMed ID: 10.1038/s41467-021-25340-w, Oral immune dysfunction is associated with the expansion of FOXP3+PD-1+Amphiregu...
- PubMed ID: 10.1007/s11240-012-0206-x, Enhanced expression of the human CD14 protein in tobacco using a 22-kDa alpha-ze...
- PubMed ID: 31930698, Zhou Z,Liu F,Wang L,Zhu B,Chen Y,Yu Y,Wang X.Inflammation has synergistic effect...
- PubMed ID: 33500729, Shi M,Shen K,Yang B,Zhang P,Lv K,Qi H,Wang Y,Li M,Yuan Q,Zhang Y. An electropora...
- PubMed ID: 23613798, Detection of Vulnerable Atherosclerotic Plaque and Prediction of Thrombosis Even...
- PubMed ID: 28852734, ANTI-INFLAMMATORY ACTIVITY OF PLATYCODIN D ON ALCOHOL-INDUCED FATTY LIVER RATS V...
- PubMed ID: 25009584, Chinese medicinal formula, Qinggan Huoxue Recipe protects rats from alcoholic li...
- PubMed ID: 23613625, Wang Zk, Xiao Jg, Huang Xf, Gong Yc, Li W. World J Gastroenterol. 2013 Apr 21;19...
- PubMed ID: 24681515, Liu D, Wang Y, Ye Y, Yin G, Chen L. Cell Immunol. 2014 May-Jun;289(1-2):7-14. Do...
- PubMed ID: 23346371, Huang J, Zhu C, Zhang P, Zhu Q, Liu Y, Zhu Z, Wang M, Li W, Yang G, Dong N, Liu ...
- PubMed ID: 12557030, Jiang Jx, Chen Yh, Xie Gq, Ji Sh, Liu Dw, Qiu J, Zhu Pf, Wang Zg. World J Surg. ...
*More publications can be found for each product on its corresponding product page