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- Table of Contents
Cathepsin B Antibodies
AND CTSB ELISA kits, Cathepsin B Proteins
Many biological assays use antibodies to detect Cathepsin B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cathepsin B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cathepsin B antibodies...
Designing a Western blot for Cathepsin B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CTSB Western Blot GuideCTSB Infographic by Boster Bio
All CTSB Products
Product
Figures
Specificity
Applications
Price
Anti-Cathepsin B/CTSB Antibody Picoband®
6 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01456-3
100 μg/vial
Cat # A01456-3
100 μg/vial
Human
ELISA
$399
Cat # EK0670
96 wells/kit, with removable strips.
Cat # EK0670
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK2130
96 wells/kit, with removable strips.
Cat # EK2130
96 wells/kit, with removable strips.
Human
IP, IF, IHC, ICC, WB
$370
Cat # M01456
100 μl
Cat # M01456
100 μl
Mouse
ELISA
$499
Cat # FEK0671
96 wells/kit, with removable strips.
Cat # FEK0671
96 wells/kit, with removable strips.
Mouse
ELISA
$399
Cat # EK0671
96 wells/kit, with removable strips.
Cat # EK0671
96 wells/kit, with removable strips.
Human
$628
Cat # LS001508
20 µg, 100 µg
Cat # LS001508
20 µg, 100 µg
CTSB Overview
Facts about Cathepsin B.
Cathepsin B (CTSB)
Thiol protease that is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CTSB |
| Uniprot: | P07858 |
| Entrez: | 1508 |
Family
| Belongs to: |
|---|
| peptidase C1 family |
Alternative Names
APP secretase; APPS; Cathepsin B; Cathepsin B1; CPSBamyloid precursor protein secretase; CTSB; cysteine protease; EC 3.4.22; EC 3.4.22.1
Molecular Weight
Mass (kDA):
37.822 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p23.1 |
| Sequence: | 8; NC_000008.11 (11842524..11868118, complement) |
Subcellular Localizations
Lysosome. Melanosome. Secreted, extracellular space. Apical cell membrane; Peripheral membrane protein; Extracellular side. Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells (By similarity).
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Inflammation
- Cell Invasion
- Carcinoma
- Adenocarcinoma
- Neoplasm Invasiveness
- Malignant Paraganglionic Neoplasm
- Pancreatitis
- Malignant Neoplasm Of Breast
- Cell Transformation, Neoplastic
- Lung Neoplasms
Interacting Proteins
- ADAMTSL4
- AMBP
- MLH1
- SPHK1
Pathways
- Pathogenesis
- Secretion
- Cell Death
- Localization
- Angiogenesis
- Cell Proliferation
- Proteolysis
- Autophagy
- Cell Migration
- Trypsinogen Activation
- Cell Differentiation
- Glycolysis
- Inflammatory Response
PTMs
- Cleavage
- Phosphorylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CTSB
bosterbio.com/bosterbio-gene-info-cards/CTSB
References
PMID: 3463996 by Chan S.J., et al. Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs.
PMID: 8112600 by Cao L., et al. Human gastric adenocarcinoma cathepsin B: isolation and sequencing of full-length cDNAs and polymorphisms of the gene.
6 Publications of Boster Cathepsin B Antibodies & ELISA Kits
- PubMed ID: 10.3389/fonc.2019.01239, Expression and Clinical Implications of Cysteine Cathepsins in Gallbladder Carci...
- PubMed ID: 10.1038/ctg.2017.25, Cathepsin L and B as Potential Markers for Liver Fibrosis: Insights From Patient...
- PubMed ID: 10.1002/mabi.201500014, Highly Porous Gelatin Reinforced 3D Scaffolds for Articular Cartilage Regenerati...
- PubMed ID: 27310928, Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-...
- PubMed ID: 24878992, Zhang Zy, Mai Y, Yang H, Dong Py, Zheng Xl, Yang Gs. Mol Cell Biochem. 2014 Oct;...
- PubMed ID: 24818882, Yang D, L?? X, Hong Y, Xi T, Zhang D. Biomaterials. 2014 Aug;35(24):6195-205. Do...
*More publications can be found for each product on its corresponding product page